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Tesamorelin is an FDA-approved drug for lipodystrophy, a medical condition characterized by abnormal distribution of body fat. This small molecule (known as peptide) is a synthetic analog of growth hormone–releasing factor, which means that it stimulates the pituitary gland to secrete growth hormone (GH). This mechanism is thought to play an integral role in body fat reduction since direct GH administration has fat burning effects. Tesamorelin is usually available in powder form to be mixed with a sterile liquid and is given via subcutaneous injection (between the skin and the muscle).
Growth hormone–releasing hormone (GHRH) such as tesamorelin has potent effect on brain function. Studies show that this “cognitive enhancer” may benefit people with age-related memory problems and those suffering from chronic, progressive mental deterioration:
The ability of tesamorelin to improve lipid profile can be attributed to its fat burning effect and GH-boosting properties. High quality studies support its beneficial effect on triglycerides, total cholesterol, low-density lipoprotein (bad cholesterol), and high-density lipoprotein (good cholesterol):
Studies also show that tesamorelin may benefit liver function through various important mechanisms:
Clinical trials also show that tesamorelin can bring down high blood sugar levels by promoting fat loss:
Evidence suggests that tesamorelin can help reduce one’s risk for cardiovascular diseases by improving various health parameters such as triglyceride levels and total cholesterol levels. [1] Tesamorelin also has the ability to raise the levels of high-density lipoprotein (good cholesterol). [21] An increase in HDL cholesterol is associated with significant cardiovascular disease risk reduction. [26]
Nerve injury is one of the most debilitating medical conditions and perhaps one of the most difficult to treat as it can lead to permanent impairment in motor and sensory function of the affected area. Research, however, suggests that growth hormone-based therapies such as tesamorelin treatment can speed up the rate of healing of damaged nerves. [27]
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