Fights Inflammation

Evidence suggests that the enzyme NNMT is highly associated with inflammatory conditions and related injuries, suggesting that NNMT inhibitors like 5-amino-1MQ may have an anti-inflammatory role:
1. Significantly increased levels of NNMT have been observed in the lungs and skeletal muscle of patients with chronic obstructive pulmonary disease (COPD) with muscle wasting. [9-10]
2. Increased NNMT levels were also seen in the skeletal muscle of patients with various forms of muscular abnormalities. [11]
3. Experimental studies in mice also found an increase in NNMT levels after drug-induced liver injury. [12-13]
4. A study found that NNMT production is the body’s protective compensatory response to injury, resulting in inflammatory states. [14]