Promotes Weight Loss

A good deal of evidence also suggests that aminophylline can improve body composition by reducing body fat percentage and promoting lean muscle mass:
1. In overweight men and women, application of 0.5% aminophylline cream to the waist twice a day was associated with significant reduction in waist circumference. [20]
2. In participants with fat deposits on their thighs, application of aminophylline lotion significantly reduced thigh circumference, thigh skinfold thickness, and thigh fat mass. [21]
3. Twelve weeks of 0.5% aminophylline cream administration significantly decreased waist-to-hip ratios in overweight female participants compared to male participants.[22]
4. A study found that aminophylline promotes fat loss by inducing breakdown of fat cells. [23]
5. In women with lower body fat distribution, application of aminophylline cream significantly reduced thigh fat. [24]