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Wards Off Depression

It’s probably not too surprising that Bacopa monnieri can also help ward off depression because it has beneficial effects on stress and anxiety. In fact, most studies assessing its anti-depressant effect showed positive outcome:
1. In healthy elderly participants, consumption of Bacopa monnieri at doses of 300 mg per day improved depression scores. [25]
2. Bacopa monnieri may help prevent depression by suppressing neuroinflammation, which is associated with depressive symptoms and psychiatric diseases. [26]
3. In rat model of depression, Bacopa monnieri treatment exerted antidepressant effect comparable to that of imipramine, a tricyclic antidepressant. [27]
4. In mice, Bacopa monnieri supplementation at varying doses (50, 100, and 200 mg/kg) reduced the duration of immobility times in the forced swimming test, which is indicative of an antidepressant effect. [28-30]
5. In a rat model of neuropathic pain, Bacopa monnieri reduced depressive-like behaviors by significantly reducing pain levels. [31]
6. In rats which were subjected to undergo chronic unpredictable stress, Bacopa monnieri greatly suppressed depressive-like behaviors. [32]
7. Administration of Bacopa monnieri also reduced morphine-induced depression in rats. [33]

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