Fights Cancer

Consumption of caffeine is also a safe and effective way to ward off various types of cancer. Numerous clinical trials suggest that consumption of caffeine products can dramatically reduce cancer risk:
1. Studies found that regular coffee consumption was associated with a 40% lower risk of liver cancer. [184-188]
2. Studies also found that coffee consumption was associated with a lower incidence of oral and pharynx cancer. [189-195]
3. Higher coffee consumption was also associated with a lower risk of esophageal cancer. [196-197]
4. Habitual coffee intake may help prevent cancer by reducing harmful oxidation processes in the body. [198]
5. A study found that increased caffeine intake and caffeinated coffee consumption may be protective against skin cancer. [199]
6. Multiple cell studies found that caffeine has the ability to induce programmed cell death (apoptosis) of gastric cancer cells by activating the caspase-9/−3 pathway. [200-205]
7. In patients with stage III colon cancer, higher coffee intake was associated with significantly reduced cancer recurrence and death. [206]
8. In patients with metastatic carcinoma or lymphoma, caffeine-potentiated chemotherapy was associated with greater than 30% gross tumor shrinkage and increased survival time. [207]
9. In patients with desmoplastic small round cell tumor (DSRCT), a rare tumor of the abdominal cavity, caffeine-assisted chemotherapy prevented local relapse and distant metastases. [208]
10. In the Prostate, Lung, Colorectal, and Ovarian cancer screening trial, researchers found a decreased risk of endometrial cancer for coffee intake. [209]
11. In Japanese women, daily drinking of 1-2 cups and 3 or more cups of coffee per day reduced the risk of endometrial cancer. [210]
12. The Three‐Prefecture Cohort Study found that increased coffee consumption resulted in a decreased risk of all‐sites cancer incidence and mortality. [211]
13. A study involving 206 096 participants found that coffee consumption may decrease the risk of prostate cancer. [212]
14. An analysis of multiple studies also found that coffee consumption may lower the risk of fatal prostate cancer. [213-216]
15. A study found that countries which commonly consumed green tea have low ovarian cancer incidence. [217]
16. In females, high black tea intake reduced the risk of bladder cancer. [218]
17. In human glioma cells, a type of tumor in the brain or the spine, treatment with caffeine induced cell cycle arrest and caspase-dependent cell death, supporting its potential use in chemotherapeutic options for malignant cancer cells. [219-221]
18. In human sarcoma cells, a malignant tumor of the connective tissue, caffeine showed growth-inhibitory effect through induction of cell death. [222]
19. In human breast cancer cells, caffeine treatment prevented breast tumor growth/recurrence through inhibition of the procarcinogenic effects. [223]
20. In human lung cancer cell lines, caffeine promoted cell death through a cell cycle-independent mechanism. [224]
21. In human leukemia cells, caffeine induced cell cycle arrest and programmed cell death. [225]
22. In mice, administration of green tea, coffee and caffeine inhibited the development of skin cancer by inducing programmed cell death of tumors. [226]
23. In mice exposed to ultraviolet B radiation, caffeine prevented cancer progression through inhibition of cell growth signal. [227]

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