Contrave-induced weight loss is known to play a role in reducing high cholesterol levels. Studies found that patients taking this drug had better lipid profile:
1. In obese patients, naltrexone/bupropion combination significantly reduced the levels of low-density lipoprotein (bad cholesterol) and increased the levels of high-density lipoprotein (good cholesterol). 
2. In overweight and obese patients, daily treatment with contrave increased high-density lipoprotein cholesterol and decreased triglycerides. 
3. In obese adults undergoing weight management, contrave administration also increased high-density lipoprotein cholesterol. 
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