Not only does contrave improves body composition but it can also help bring down high levels of blood sugar. Evidence suggests that it can be beneficial for diabetic patients as well as those with chronic elevated blood sugar levels:
1. In overweight and obese patients with type 2 diabetes, treatment with 32 mg naltrexone sustained-release (SR)/360 mg bupropion SR (NB) was associated with improvement in blood sugar control as evidenced by greater reduction in hemoglobin A1c (HbA1c). 
2. In diabetic patients, naltrexone/bupropion therapy decreased HbA1c approximately 0.5% more than placebo. 
3. In overweight and obese patients, contrave also decreased major cardiovascular risk factors such as high blood sugar. 
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