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DHEA and Cancer

DHEA does not only have anti-aging capability but it also has potent anti-cancer properties. There is strong scientific evidence that this hormone is capable of destroying various cancer cell types, thereby preventing its spread in different body parts (metastasis). Results from numerous studies show that DHEA fights cancer through various mechanisms:
1. In patients with colon cancer, DHEA prevents the metastatic progression of colon cancer cells by targeting the prenylation pathway, a process that contributes to the spread of cancer cells. [285]
2. In cancer patients, DHEA administration at a dose of 25-50 mg daily induces significant normalization of abnormal cancer parameters. [286]
3. DHEA inhibits the growth and reproduction of different human breast cancer cell lines by inhibiting the production of inflammatory substances and proteins related with cell migration and metastasis. [287-288]
4. In postmenopausal women, DHEA inhibits the growth of breast cancer cells. [289]
5. In patients with advanced prostate cancer who are unresponsive to chemotherapy and other standard treatment regimens, DHEA significantly improves symptoms. [290]
6. Dietary supplementation with 0.6% DHEA significantly inhibits pancreatic cancer cell growth. [291]
7. DHEA inhibits the growth, reproduction, and migration of human uterine cervical cancers by inducing programmed cell death. [292-293]

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