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DHEA and Cardiovascular Health

DHEA appears to play a major role in cardiovascular function and deficiency in this vital hormone may compromise heart health. In fact several high quality studies found a strong link between DHEA deficiency and higher incidence of heart diseases in both men and women. [193-207] This suggests that replacing DHEA to youthful levels can help boost heart health and prevent various fatal heart diseases. A number of clinical trials support the beneficial effects of DHEA replacement therapy on the cardiovascular system:
1. In patients with coronary heart disease, DHEA inhibits human platelet aggregation and dissolves blood clots. [208]
2. In patients with cardiovascular disease, DHEA relaxes the blood vessels of the heart, thereby improving blood flow and function. [209]
3. In patients with coronary heart disease, DHEA replacement therapy significantly decreases the levels of fibrinogen, a protein associated with blood clotting. [210]
4. In patients with cardiovascular disease, higher DHEA levels are associated with better prognosis. [211]
5. In postmenopausal women, long-term treatment with DHEA lowers cardiovascular risk by improving insulin sensitivity and cholesterol levels. [212-213]

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