DHEA and Cholesterol Levels

Cholesterol is required for DHEA production. In fact, the process by which DHEA is produced starts when cholesterol enters the “powerhouse” of cells known as mitochondria. [362] Researchers believe that this process may help lower cholesterol and increase DHEA levels in the body, thereby boosting overall health. Results from several studies support the beneficial effects of DHEA supplementation on cholesterol levels:
1. In overweight individuals, higher DHEA levels are associated with lower cholesterol levels. [363]
2. In older women with frailty characteristics, DHEA supplementation improves total cholesterol and low-density lipoprotein (LDL) levels. [364]
3. In men aged 41-60 years, DHEA therapy at a dose of 150 mg daily for 40 days reduces total cholesterol levels. [365]
4. In postmenopausal women, DHEA supplementation has favourable effect on cholesterol levels. [366]

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