Estrogen and Bone Health

The body constantly builds and remodels bone. However, after menopause, this process slows down causing women to lose as much as 20% of their bone mass. [4] As a result, postmenopausal women begin to experience osteoporosis, fractures, and other bone disorders. [5-7] In aging men, low estrogen levels can also increase their risk of developing bone problems. [8-10] An overwhelming body of clinical evidence suggests that this age-related bone loss can be prevented and treated with ERT:
1. In both men and women, estrogen regulates bone metabolism and maintains bone formation. [11-13]
2. In postmenopausal women, low-dose ERT as well as the standard dose ERT is associated with significant reduction in the incidence of osteoporosis and fractures. [14-23]
3. In postmenopausal women, ERT significantly increases bone mineral density (BMD) of different skeletal sites without any adverse side effects. [24-37]
4. In postmenopausal women, discontinuation of ERT results in acceleration of bone breakdown, decrease in BMD and eventual loss of anti-fracture efficacy. [38-44]
5. In early and late postmenopausal women, ERT slows bone breakdown and increases bone BMD at all skeletal sites. [45-46]
6. In postmenopausal women with osteoporosis and other bone disorders, ERT appears to be safe and effective in increasing bone mass. [47-55]
7. In humans and animals with bone fractures, ERT accelerates bone healing and prevents further bone breakdown. [56-67]

before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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