Estrogen and Cholesterol Levels

Cholesterol levels spike in men and women with advancing age. For women, however, this age-related change is striking at the menopausal transition stage. With falling estrogen levels, high-density lipoprotein (HDL) cholesterol, also known as the “good cholesterol”, starts to decline. On the other hand, the age-related decline in estrogen levels increases low-density lipoprotein (LDL) cholesterol, also known as the “bad cholesterol”. These changes in cholesterol levels are very detrimental to health because it drastically increases one’s risk of developing fatal medical conditions such as heart disease, stroke, cancer, diabetes, and hypertension. While diet and lifestyle modifications can be beneficial in improving cholesterol profile, there is strong evidence that ERT may also help normalize cholesterol levels:
1. In healthy postmenopausal women, oral estrogen supplementation increases HDL cholesterol levels by 15-18%. [404]
2. In healthy postmenopausal women who had surgical removal of the uterus, both oral and transdermal estradiol for 4 weeks increase HDL by 7.1%. [405-406]
3. In healthy premenopausal women, ERT increases HDL and decreases LDL levels without any adverse side effects. [407-418]
4. In postmenopausal women with elevated cholesterol levels, ERT produces significant and therapeutic reductions in LDL cholesterol. [419-421]
5. Oral estrogen administration for 6 months significantly increases HDL and decreases LDL in menopausal women, making it the most effective route. [422-423]

before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

Call 800-277-4041 for a Free Consultation

What to expect during your consultation:
  • Usually takes 15-30 minutes
  • Completely confidential
  • No obligation to purchase anything
  • We will discuss your symptoms along with your health and fitness goals
  • Free post-consult access for any additional questions you may have
Contact Us Page

Genemedics® Health Institute is a global premier institute dedicated to revolutionizing health and medicine through healthy lifestyle education, guidance and accountability in harmony with functional medicine. Our physician-supervised health programs are personally customized to help you reach your health and fitness goals while looking and feeling better than ever.