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Estrogen Replacement Therapy (ERT)

Over time, the gradual decline in women’s estrogen levels can lead to debilitating signs and symptoms which can ultimately impair one’s quality of life. Women who had their uterus surgically removed (hysterectomy) can also experience these detrimental effects. Fortunately, for those suffering from estrogen deficiency, ERT can be used to increase estrogen levels, alleviate unpleasant symptoms, and improve overall quality of life.
There are different ways ERT is administered. These include:

  • Oral – The oral route is the most frequently utilized method of ERT because it effectively delivers estrogen into the bloodstream. Estrogen tablets are relatively convenient and inexpensive for most women.
  • Transdermal patches (Skin patches) – Skin patches bypass the liver and are recommended for patients who do not respond to estrogen tablets. This route of administration allows the estrogen to be gradually absorbed by the skin.
  • Transdermal gels or creams – This method makes use of a measured amount of gel or cream that is applied on the skin. Application of transdermal gel also allows the estrogen to be gradually absorbed into the bloodstream.
  • Sublingual – This route involves placing estrogen tablets under the tongue. It is absorbed through the lining of the mouth into the blood vessels and then into the bloodstream.
  • Intramuscular injections – Injection of estrogen into the muscles is the most common method of ERT used by many physicians. The hormone is usually mixed with a substance to allow slow release into the bloodstream once injected.
  • Subcutaneous implantations – This method involves implantation of estrogen pellets into the tissue layer between the skin and the muscle at 3-6-month interval. The most commonly used body areas are the abdomen or buttocks.

Potential candidates for ERT usually undergo measurement of estrogen levels first through comprehensive saliva, blood, urine and serum test. By determining the baseline estrogen levels, the ERT physician will be able to customize a treatment plan that is tailored to the individual needs of the patient.

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At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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