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Estrogen and Weight Loss

In addition to diet, lifestyle, and genetic factors, the aging process can also contribute to weight gain. In fact, the older we get, the more difficult it is to lose weight. Not only does our metabolism slows down, but also the production of estrogen. In women, the age-related decline in estrogen levels causes their bodies to look for other sources of estrogen, which can be found in fat cells. [114] As a result, their bodies learn to convert more calories into fat, leading to weight gain. In men, the age-related decline in estrogen causes fat accumulation, which in turn results in weight gain. [115] While diet and lifestyle modifications are critical elements to weight loss, there is increasing evidence that restoring estrogen to youthful levels through ERT may help you achieve healthier weight:
1. In obese menopausal women, three months of ERT significantly reduces weight by increasing energy expenditure. [116]
2. In healthy postmenopausal women, both intranasal and oral estrogen therapy promotes weight loss by increasing the levels of leptin, a hormone that inhibits hunger. [117-127]
3. In menopausal women, ERT lowers visceral adipose tissue (fatty tissue) by improving the body’s response to insulin. [128-129]
4. In postmenopausal women, ERT reduces weight and abdominal fat by lowering cholesterol levels. [130-131]
5. In postmenopausal women, ERT is associated with a significant reduction in body mass index (BMI). [132-133]
6. In rats, estrogen prevents weight gain by regulating body adiposity and fat distribution. [134-137]

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At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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