Protects the Liver

Evidence suggests that glycyrrhetinic acid has a protective effect on liver injury through its anti-inflammatory activity:
1. A study found that glycyrrhetinic acid could prevent drug-induced liver injury and disruption of bile acid metabolism in humans. [53]
2. Pretreatment of liver cells with glycyrrhetinic acid protects against aflatoxin-induced oxidative stress. [54]
3. In mice with liver injury caused by Propionibacterium acnes, glycyrrhetinic acid treatment inhibited the activation and proliferation of liver-infiltrating CD4(+) T cells and reduced the production of inflammatory substances such as interferon-gamma and tumor necrosis factor-alpha. [55]
4. In rats, low-dose glycyrrhetinic acid (50 mg/kg) exhibited a protective effect against Triptolide-induced liver injury through its anti-inflammatory, antioxidant, and antiapoptotic properties. [56-57]
5. In mice, ingestion of glycyrrhetinic acid prevented accumulation of fats in the liver by protecting mitochondria against oxidative stress. [58]
6. In rats, glycyrrhetinic acid treatment reduced endotoxin-induced acute liver injury after partial hepatectomy (surgical removal of a part of the liver). [59]
7. In rats, glycyrrhetinic acid treatment prevented liver injury by inhibiting the production of proteins involved in liver scarring. [60-62]
8. In mice, glycyrrhetinic acid attenuated acetaminophen-induced liver injury. [63]

before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

Call 800-277-4041 for a Free Consultation

What to expect during your consultation:
  • Usually takes 15-30 minutes
  • Completely confidential
  • No obligation to purchase anything
  • We will discuss your symptoms along with your health and fitness goals
  • Free post-consult access for any additional questions you may have
Contact Us Page

Genemedics® Health Institute is a global premier institute dedicated to revolutionizing health and medicine through healthy lifestyle education, guidance and accountability in harmony with functional medicine. Our physician-supervised health programs are personally customized to help you reach your health and fitness goals while looking and feeling better than ever.