During sleep, the body releases a cascade of hormones that are necessary for recovery and growth. One of the most important hormones released during this process is IGF-1. The age-related decline in IGF-1 leads to the development of sleep problems and poor sleep quality in both men and women. In fact, studies have shown that low levels of IGF-1 were associated with poor sleep quality and prevalence of sleeping difficulties. [284-288] On the other hand, higher levels of IGF-1 are associated with improved sleep quality and quantity. 
On the other hand, studies show that higher levels of IGF-1 were associated with improved sleeping pattern and sleep quality. [290-293] This may be the reason why restoring IGF-1 levels in older patients through hormone replacement therapy has been shown to improve energy levels, emotions and sleep quality. 
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