Aside from achieving lean muscle mass, ipamorelin administration can also help maintain a healthy skeletal frame and prevent various bone disorders. Studies assessing the beneficial effects of ipamorelin on bone health have shown positive results:
1. In GH-deficient children, administration of growth hormone releasing peptides such as ipamorelin increases bone growth velocity. [29-33]
2. In rats, ipamorelin administration induces longitudinal bone growth. 
3. In adult female rats, ipamorelin administration increases bone mineral content without any side effects or toxicities. 
4. In adult rats, simultaneous administration of ipamorelin counteracts glucocorticoid-induced decrease in bone formation. 
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