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Maintains a Healthy Heart

Recent human clinical trials and animal studies show that ipamorelin and other growth hormone releasing peptides have cardioprotective effects that can help combat various heart diseases:
1. In patients with heart disease, administration of growth hormone releasing peptide improves cardiac output and ventricular mechanical work. [47]
2. In patients with coronary artery disease undergoing bypass surgery, administration of growth hormone releasing peptide increases left ventricular ejection fraction. [48]
3. In human subjects, administration of growth hormone releasing peptide helps protect against heart damage induced by lack of oxygen. [49]
4. In healthy volunteers, acute intravenous administration of growth hormone releasing peptide induces clear and prompt increase in left ventricular ejection fraction. [50-51]
5. In patients with heart failure, ipamorelin administration increases heart muscle contractions by boosting the levels of IGF-1. [52-54]
6. In rats, administration of growth hormone releasing peptide protects against heart injury caused by lack of oxygen. [55]
7. In rats subjected to experimental myocardial infarction, administration of growth hormone releasing peptide increases blood volume pumped by the left ventricle of the heart. [56]
8. In rats, growth hormone releasing peptide administration increases the strength of muscular contraction of the heart. [57]
9. In rats, growth hormone releasing peptide administration prevents heart failure by protecting against radical damage. [58]
10. In hamsters with dilated cardiomyopathy, 4-week treatment with growth hormone releasing peptide attenuates left ventricular dysfunction and dilation. [59]
11. In dogs with decreased blood supply to the heart, growth hormone releasing peptide administration prevents death by increasing heart wall thickness, which is suggestive of improved blood circulation. [60]
12. In pigs, growth hormone releasing peptide administration exhibits antioxidant effects, which in turn reduce damage to the heart muscle. [61]

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