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Strengthens the Immune System

There is increasing evidence that ipamorelin may help boost immune function through various important mechanisms:
1. Administration of growth hormone releasing peptide may help improve the quality of life of cancer patients by correcting nutritional and metabolic states. [73]
2. In patients with growth hormone deficiency, boosting GH levels through growth hormone releasing peptide administration increases the levels of white blood cells, T cells and B cells of the immune system. [74-75]
3. In rats, administration of growth hormone releasing peptides such as ipamorelin counters inflammation via AKT1-activated pathway and reduces programmed cell death (apoptosis) while combating oxidative stress. [76-77]
4. In animal models, growth hormone releasing peptide administration protects against multiple sclerosis, nerve damage, and brain diseases. [78-81]
5. In mice, growth hormone releasing peptide administration enhances antibody titers against various harmful microorganisms. [82]
6. As a growth hormone releasing peptide, ipamorelin helps strengthen the immune system by boosting GH levels. 83-95]
7. As a growth hormone stimulant, ipamorelin enhances immune function by stimulating T and B cells proliferation and immunoglobulin synthesis, and aiding in the maturation of stem cells and modulation of the inflammatory response. [96]
8. By increasing GH levels, ipamorelin improves the functional activity of circulating phagocyte cells (cells that engulf foreign bodies). [97]
9. Ipamorelin can also improve the cytotoxic activity mediated by natural killer cells. [98-100]
10. By boosting GH levels, ipamorelin can increase the production of various immune system cells such as IL-1β, TNF-α, IL-6, and cytokines. [101-102]
11. Growth hormone secretagogues such as ipamorelin enhance the development of the thymus, a gland that produces T cells for the immune system. [103-110]
12. Administration of growth hormone secretagogues increases tumor resistance in mice. [111]

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