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Strengthens the Immune System

Aside from its potent anti-inflammatory properties, studies show that KPV may help boost the immune function by positively affecting the production of immune system cells and other mechanisms:
1. As a C-terminal tripeptide of α-MSH, studies found that KPV has potent antipyretic activity (lowers body temperature) in experimental fever. [33-42]
2. Studies show that KPV prevents fever by targeting the hypothalamus, the brain region that controls temperature, and by reducing pyrogens (substances that cause fever). [43-49]
3. A 2007 study published in Gene Therapy found that KPV treatment was associated with high frequency of CD4+CD25+ regulatory T cells. [50]
4. In rats, KPV injections twice daily significantly reduced the clinical and histological signs of adjuvant-induced arthritis. [51]
5. In animal models of human autoimmune inflammatory eye diseases such as uveitis or retinitis, KPV significantly reduced symptoms and inflammatory substances. [52-56]
6. In animal model of experimentally induced acute pancreatitis, KPV treatment reduced pancreas islet cell apoptosis (programmed cell death. [57-59]

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