Improves Mood

Numerous high quality studies show that L-theanine plays a key role in mood support by positively affecting the production of neurotransmitters:
1. In patients with major depressive disorder, L-theanine administration for 8 weeks improved depressive symptoms, anxiety, sleep disturbance and cognitive impairments. [14]
2. In patients with schizophrenia, supplementation with 400 mg L-theanine along with regular medications for 8 weeks resulted in significant reductions in anxiety and general symptoms of psychopathology. [15]
3. A dose of 250 mg per day of L-theanine also improved symptoms and sleep in schizophrenic patients. [16]
4. Combination of L-theanine and the hormone pregnenolone improved negative symptoms in schizophrenic patients. [17]
5. Administration of 200 mg of L-theanine was associated with increased brain alpha waves (stimulate creativity and reduce depression) and prolonged periods of relaxation. [18-19]
6. L-theanine may also help improve mood by stimulating production of the relaxing neurotransmitter Gamma-Aminobutyric Acid (GABA). [20]
7. In patients with generalized anxiety disorder, L-theanine treatment was associated with improved symptoms. [21]
8. In animal models, L-theanine supplementation reduced symptoms of anxiety. [22]
9. In a chronic unpredictable mild stress rat model, L-theanine ameliorated the depressive-like behaviors. [23]