Fights Inflammation

Aside from its immune-boosting properties, LL-37 also has potent anti-inflammatory activity according to high quality studies:
1. In patients who had surgical removal of the tonsils, those with high levels of LL-37 had lesser inflammation compared to those with low LL-37. [17]
2. LL-37 suppresses the translocation of NF-kB to the nucleus, which creates an anti-inflammatory effect. [18]
3. In mice, LL-37 administration reduced the risk of inflammatory disease. [19]
4. LL-37 reduces inflammation by modulating inflammatory pathways in the body. [20-22]
5. In human gum cells, LL-37 strongly reduced the levels of pro-inflammatory cytokines and chemokines. [23]
6. LL-37 also modulates the inflammatory and host defense response of human white blood cells. [24]