Improves Cardiovascular Health

There’s also a great deal of evidence supporting the beneficial role of metformin on cardiovascular health:
1. Metformin has been shown to prevent the fragmentation of mitochondria in endothelial cells which is associated with atherosclerosis (plaque formation). [78]
2. In patients with heart failure, metformin administration reduced the risk of deaths by 75%. [79]
3. A study demonstrated that metformin administration in patients with heart disease reduced the risk of heart attack, abnormal heart rhythm, and related deaths. [80]
4. In overweight patients with type 2 diabetes, monotherapy of metformin was correlated with decreased risk of cardiovascular disease. [81]
5. A study found that metformin may help lower the risk of cardiovascular disease by reducing the levels of free fatty acid, triglyceride, and soluble vascular cell adhesion molecule-1 (sVCAM-1). [82]
6. In patients with type 2 diabetes, metformin treatment reduced the risk of coronary heart disease by improving cholesterol levels. [83-84]
7. Metformin may also help combat heart disease by suppressing inflammation and coagulation. [85]
8. In male participants, metformin treatment was associated with reduced risk of atherosclerosis (coronary artery calcium). [86]
9. In patients with type 2 diabetes, combination of insulin and metformin reduced the risk of cardiovascular disease by 40%. [87]
10. Metformin can help improve endothelial cell function, which involves the inner lining of the heart, by combating stress and inflammatory response. [88-89]
11. In patients with ischaemic cardiomyopathy (weakening of heart muscle), metformin treatment was associated with reduced rates of heart attack, chest pain, and related deaths. [90]
12. Another mechanism by which metformin improves cardiovascular health is by increasing fat redistribution. [91-92]

before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

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