Improves Cognitive Function

Emerging evidence suggests that metformin may play an important role in preserving cognitive function:
1. In the Singapore Longitudinal Aging Study, the use of metformin was associated with a 51% reduced risk of cognitive impairment. [93]
2. A large observational study of patients with type 2 diabetes reported lower rates of dementia in metformin-treated groups compared to those treated with other antidiabetic drugs. [94]
3. In patients with type 2 diabetes, metformin administration improved cognitive performance. [95]
4. Metformin may help prevent Parkinson’s disease and Alzheimer’s disease by reducing the levels of abnormal protein aggregates in the brain. [96-99]
5. Metformin exerts its neuroprotective effects via AMPK activation. [100-103]
6. Metformin can also improve neurological deficits through various important mechanisms such as decreasing oxidative stress, preventing brain mitochondrial dysfunction, and increasing brain-derived neurotrophic factor levels. [104-107]
7. A cell study found that metformin may help enhance spatial memory by promoting formation of new nerve cells in the brain. [108]

before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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