The mitochondria are considered as the “powerhouses of cells”. They are organelles that work like the digestive system which ingests nutrients, breaks them down, and produces fuel or energy for the cells’ biological functions. The mitochondria also pass down information via several signaling molecules in order to enhance communication between each cell. Mitochondrial ORF of the twelve S c (MOTS-c) is one of the mitochondrial-derived peptides (MDPs) that plays an integral role in a wide array of metabolic functions such as glucose metabolism, muscle synthesis, and maintenance of metabolic homeostasis (balance). Interestingly, studies show that MOTS-c holds much potential as a therapeutic option for a multitude of medical conditions because of its unique ability to positively affect various bodily functions.
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