MK-677, also known as ibutamoren or ibutamoren mesylate, belongs to a group called growth hormone secretagogues. They are substances that boost the production of growth hormone (GH). MK-677 can also increase the production of insulin-like growth factor 1 (IGF-1), a hormone similar in molecular structure and function to insulin. The ability of MK-677 to boost the levels of GH and IGF-1 is associated with a wide array of health benefits. The exact mechanism by which MK-677 exerts these effects is by mimicking the action of ghrelin (hunger hormone) and binding to one of the ghrelin receptors (GHSR) in the brain. [1] Interestingly, GHSR is located in certain regions of the brain that regulate appetite, mood, pleasure, and cognitive function. [2] Because of this, researchers believe that MK-677 can have beneficial effects on these functions. In addition, MK-677 is also classified as a selective androgen receptor modulator (SARM), a class of therapeutic compounds similar in function with anabolic agents, but with lesser side effects. This makes MK-677 a safe and effective form of GH and IGF-1 replacement therapy.

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