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GENEMEDICS NUTRITION
MK-677 is frequently used as an anabolic substance, which means that it has the ability to increase muscle mass and strength while promoting fat loss. Studies show that this powerful compound can help improve body composition and prevent muscle wasting related to old age and other medical conditions:
1. In obese males, oral treatment with MK-677 increases fat-free mass by boosting basal metabolic rate (BMR), the rate at which the body uses energy while at rest. [3]
2. Several high quality studies show that higher GH levels are strongly linked with increased muscle mass and strength in the elderly, suggesting that MK-677 supplementation may have positive effect. [4-13]
3. Several lines of evidence also suggest that higher IGF-1 levels are associated with increased muscle mass and strength in the older population. [14-22]
4. In patients with muscle wasting, MK-677 reverses diet-induced nitrogen wasting without any clinically adverse side effects. [23]
5. In patients recovering from hip fracture, MK-677 treatment improves gait speed and stair climbing power, which is suggestive of improved muscle function. [24]
6. In healthy older adults, 12 months of MK-677 treatment significantly increases fat-free mass without any adverse side effects. [25]
7. In GH-deficient adults, MK-677 administration improves body composition by increasing IGF-1 levels. [26]
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