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Improves Sleep Quality

The aging population is highly at risk for sleeping problems and disorders that can significantly affect their quality of life. Whether it is age-related or caused by a certain medical condition, MK-677 supplementation may help improve sleep quality and quantity according to numerous clinical research:
1. In both younger and elderly subjects, MK-677 treatment for 14 days improves sleep quality by increasing rapid eye movement (REM) sleep duration by 50%. [57]
2. In healthy older adults, oral administration of MK-677 (25 mg) once daily improves Pittsburgh Sleep Quality Index, a measure of sleep. [58]
3. In normal men, administration of growth hormone secretagogue increases slow-wave sleep (SWS), which is often referred to as deep sleep. [59]
4. In young healthy men, intravenous injections of growth hormone secretagogue during sleep consistently stimulate slow-wave sleep, suggesting that MK-677 may help improve sleep quality. [60]
5. In normal young males, growth hormone secretagogue administration increases stage 2 sleep. [61]
6. Higher GH levels are strongly associated with improved deep sleep stage, indicating that MK-677 supplementation may have positive effect on sleep. [62-67]
7. Higher IGF-1 levels are also linked with better sleep, suggesting that MK-677 supplementation may have beneficial effects. [68-78]
8. Studies on rats show that growth hormone secretagogue administration activates sleep regulatory neurons in the brain. [79]
9. In obese patients, growth hormone secretagogue administration improves stage 2 sleep by reversing GH deficiency. [80-81]

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At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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