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Maintains Healthy Skeletal Frame

Aside from improving body composition, MK-677 also has the ability to maintain healthy bones and prevent various bone disorders such as osteoporosis and fractures. There is strong scientific evidence supporting the beneficial effects of MK-677 on overall bone health:
1. In healthy obese male, MK-677 treatment for 2 weeks improves bone turnover (total volume of bone formed and broken down). [27]
2. In elderly adults (65 years or older), oral MK-677 treatment daily for 2 weeks improves bone building by increasing osteocalcin, a marker of bone turnover. [28]
3. In postmenopausal women with osteoporosis, MK-677 treatment for 12 months improves bone mineral density in the femoral neck. [29]
4. In healthy and functionally impaired elderly adults, once daily dosing with MK-677 stimulates bone turnover. [30]
5. In patients recovering from hip fracture, MK-677 treatment is associated with fewer falls and improved functional measures. [31]
6. MK-677 improves bone health by increasing the activity of osteoblasts (bone cells). [32]
7. By increasing GH levels, MK-677 can significantly lower the risk of osteoporosis, fractures, and other bone disorders. 33-45]
8. By boosting IGF-1 levels, MK-677 also helps lower the prevalence of various bone disorders. [46-56]

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