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Combats Fatigue

Modafinil can also boost energy levels by combating the effects of fatigue on the body. There is strong scientific evidence supporting the anti-fatigue properties of modafinil:
1. In patients with multiple sclerosis, modafinil administration improved fatigue, focused attention, and dexterity without any adverse side effects. [95-104]
2. In sleep-deprived patients who were subjected to sustained mental work, modafinil administration improved fatigue with fewer side effects. [105-106]
3. In narcolepsy patients who were switched from psychostimulants, administration of modafinil at 200-400 mg once daily for 6 weeks improved quality of life and subjective feelings of vigor and reduced fatigue. [107]
4. In patients suffering from Parkinson’s disease fatigue, modafinil treatment improved symptoms compared to placebo. [108]
5. In patients suffering from fatigue associated with stroke, modafinil treatment improved scores on the Fatigue Severity Scale and in some subscales of the stroke-specific quality of life questionnaire. [109-110]
6. Twelve weeks of modafinil augmentation relieved fatigue in patients with major depressive disorder. [111]
7. Modafinil administration helped patients with chronic fatigue syndrome recover. [112]
8. In patients receiving chemotherapy, modafinil relieved fatigue associated with the treatment. [113]
9. In patients with primary biliary cirrhosis, modafinil administration at a dose of 100 mg per day significantly improved fatigue severity. [114]
10. In patients with sarcoidosis, a disabling inflammatory condition affecting multiple organs, modafinil administration relieved fatigue. [115]

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