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Treats Excessive Sleepiness and Improves Sleep Quality

With its beneficial effect on neurotransmitters, studies show that modafinil can help treat narcolepsy and improve one’s quality of life:
1. In patients with excessive daytime sleepiness associated with narcolepsy, long-term modafinil treatment significantly improved disease severity. [1-16]
2. In patients with chronic shift work sleep disorder, modafinil significantly improved functioning and quality of life. [17-21]
3. Treatment with 200 mg of modafinil reduced extreme sleepiness in patients with chronic shift work sleep disorder and resulted in significant improvement in work performance. [22]
4. In patients with excessive daytime sleepiness caused by Parkinson’s disease, modafinil administration at a dose of 200 mg per day significantly reduced subjective sleepiness. [23-30]
5. In patients with myotonic dystrophy, a genetic disorder that causes progressive loss and weakening of muscles, modafinil reduced excessive daytime sleepiness and improved mood. [31-33]
6. Either monotherapy or combination therapy, modafinil reduced sleepiness and fatigue in patients with major and bipolar depression. [34-39]
7. In patients taking opioids and antipsychotics, modafinil reduced subjective sleepiness without disrupting sleep pattern. [40-43]
8. In patients with sleep apnea syndrome, modafinil administration improved measures of sleepiness. [44]
9. In patients with excessive sleepiness associated with obstructive sleep apnea/hypopnea syndrome, modafinil improved night-time wakefulness without disrupting daytime sleep. [45-56]
10. In patients with traumatic brain injury, modafinil ameliorated excessive daytime sleepiness. [57]
11. In patients with multiple sclerosis, modafinil treatment for three years or more reduced excessive daytime sleepiness. [58-60]
12. In patients with major depressive disorder who do not respond to antidepressant therapy, modafinil augmentation rapidly (within 1 week) and significantly improved sleep quality. [61-63]
13. In patients subjected to sleep deprivation, modafinil administration every 8 hours for three days resulted in a satisfactory level of vigilance, both subjective and objective, as evidenced by total absence of microsleep episodes. [64]
14. In patients with excessive daytime sleepiness related to narcolepsy, modafinil was found to be effective than methylphenidate, a drug used to treat narcolepsy. [65]
15. In chronic cocaine users, morning-dosed modafinil promoted nocturnal sleep, normalized sleep architecture, and decreased daytime sleepiness. [66]

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At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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