Naltrexone can also help achieve healthier weight, thus, reducing one’s risk for obesity-related diseases. Studies show that this drug works by reducing food intake:
1. In obese men, increasing doses of naltrexone (25 to 200 mg) given over 4 consecutive days reduced food intake by 30%. 
2. Long-term therapy with naltrexone (8 weeks) reduced body weight of obese women by an average of 1.7 kg. 
3. Administration of naltrexone alone in obese patients significantly reduced body weight. 
4. In patients with damaged metabolism, naltrexone treatment resulted in restoration of energy expenditure. 
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