Reduces Insulin Resistance

Insulin resistance is a condition in which the cells of the body do not respond properly to the effects of the hormone insulin. As a result, blood sugar levels become elevated. Chronic elevation in blood sugar can be life-threatening as it can lead to nerve damage, vision problems, and impaired kidney function. Interestingly, studies have shown that naltrexone can help improve insulin resistance and normalize blood sugar levels:
1. In obese individuals, naltrexone therapy reduced hemoglobin A1c (HbA1c), a measure of blood sugar level. [47]
2. In obese women with polycystic ovary syndrome (PCOS), naltrexone improved insulin resistance after 3 and 6 months of treatment. [48]
3. Naltrexone also improved fasting serum insulin in women with PCOS, suggesting that the hormone is effectively utilized by their bodies. [49]
4. In diabetic women with severe and chronic eating disorders, naltrexone improved blood sugar control. [50]
5. In normal obese patients, long-term naltrexone treatment reduced fasting insulin levels. [51]
6. In women with insulin resistance related to elevated male sex hormones, long-term treatment with naltrexone dramatically reduced blood sugar levels. [52]