The ability of tesamorelin to improve lipid profile can be attributed to its fat burning effect and GH-boosting properties. High quality studies support its beneficial effect on triglycerides, total cholesterol, low-density lipoprotein (bad cholesterol), and high-density lipoprotein (good cholesterol):
1. In HIV patients with abdominal fat accumulation, subcutaneous injection of tesamorelin at a dose of 2 mg significantly improved triglycerides and total cholesterol levels. 
2. Administration of tesamorelin in HIV-infected patients resulted in greater reduction in triglycerides compared to placebo treatment. 
3. Treatment of type 2 diabetic patients with tesamorelin for 12 weeks significantly reduced total cholesterol and low-density lipoprotein. 
4. In HIV-infected patients with excess abdominal fat, tesamorelin treatment increased the levels of high-density lipoprotein. 
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