GENEMEDICS APP

GENEMEDICS NUTRITION

Pregnenolone and Mood

Decreased levels of pregnenolone are strongly linked with depressed mood. [83-84] Because depression can be very challenging to treat, with current medications requiring months before its therapeutic effects are achieved, research into pregnenolone on mood can be a game-changer. Interestingly, clinical studies assessing the beneficial effects of pregnenolone on mood, depression, anxiety, and other mental disorders show positive results:
1. In women with bipolar disorders, elevated levels of pregnenolone are associated with stable mood state. [85]
2. Pregnenolone boosts mood through activation of neurocircuits that control emotion. [86]
3. Blocking pregnenolone production impairs social and emotional functioning. [87]
4. In patients with bipolar disorder, recurrent major depressive disorder, and history of substance abuse/dependence, pregnenolone administration reduces symptoms of depression. [88-90]
5. Depressive disorders are caused by neuronal abnormalities in brain microtubule function. [91] By boosting the production and stability of tubules, pregnenolone promotes growth of neurons, thus fighting depression. [92]
6. Individuals with generalized anxiety disorder appear to have lower levels of pregnenolone than those without anxiety. [93]
7. Preclinical findings suggest that pregnenolone plays a major role in anxiety and depression-regulatory mechanisms. [94-95]
8. Patients experiencing a depressive episode, either unipolar or bipolar type, had lower levels of pregnenolone than healthy controls. [96]
9. Pregnenolone administration reduces self-reported anxiety. [97]
10. In adults with autism spectrum disorder, pregnenolone reduces irritability. [98]
11. Pregnenolone enhances mood by activating the brain chemical GABA. [99]

testimonial
before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

Call 800-277-4041 for a Free Consultation

What to expect during your consultation:
  • Usually takes 15-30 minutes
  • Completely confidential
  • No obligation to purchase anything
  • We will discuss your symptoms along with your health and fitness goals
  • Free post-consult access for any additional questions you may have
Contact Us Page
Sending

Genemedics® Health Institute is a global premier institute dedicated to revolutionizing health and medicine through healthy lifestyle education, guidance and accountability in harmony with functional medicine. Our physician-supervised health programs are personally customized to help you reach your health and fitness goals while looking and feeling better than ever.