Progesterone and Inflammation

Progesterone has potent anti-inflammatory properties that can help treat and prevent a wide array of inflammatory conditions. Numerous clinical trials suggest that progesterone fights inflammation through the following important mechanisms:
1. It suppresses NF-κB and MAPK activation, which in turn inhibits the production of proinflammatory markers like COX-2, IL-6, iNOS, and TNF-α. [26-31]
2. It enhances the synthesis of brain steroids. [32]
3. It inhibits vascular permeability and the formation of granulation tissue in the early phase of the inflammation. [33]
4. It reduces cellular inflammatory response. [34]

before after

At the age of 60, I look and feel better than I ever have in my entire life! Switching my health program and hormone replacement therapy regimen over to Genemedics was one of the best decisions I’ve ever made in my life! Genemedics and Dr George have significantly improved my quality of life and also dramatically improved my overall health. I hav...

- Nick Cassavetes, 60 yrs old

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