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There’s also increasing evidence supporting the anti-cancer and antitumor properties of thymosin alpha 1:
1. By regulating cytokine secretion and repairing damaged immune system, thymosin alpha 1 may help reduce cancer incidence. [14]
2. In stage IV human breast cancer model, thymosin alpha 1 treatment was associated with significantly slow tumor growth. [15]
3. In patients with metastatic melanoma and advanced non-small cell lung cancer, thymosin alpha 1 treatment prolonged survival. [16]
4. In patients with hepatitis B virus-associated liver cancer, thymosin alpha 1 therapy improved liver function and significantly prolonged recurrence‑free and overall survival. [17]
5. Thymosin alpha 1 exerts its anti-tumor effects mainly by increasing the secretion of various T cell lymphokines, activating T4 helper cells to promote lymphocyte activity, and increasing the cytotoxicity of natural killer cells. [18-20]
6. Administration of thymosin alpha 1 in cancer patients was associated with reduced risk of dying and improved disease‐/progression‐free survival. [21]
7. In patients with metastatic lung cancer, thymosin alpha 1 treatment was associated with complete disappearance of lesions. [22]
8. A cell study found that exposure of human breast cancer cells to thymosin alpha 1 induced apoptosis (programmed cell death). [23]
9. Administration of thymosin alpha 1 in cancer patients increased the anti-tumor effect of chemotherapy while markedly reducing side effects of the treatment. [24]
10. In tumor-bearing mice, thymosin alpha 1 significantly delayed tumor growth and prolonged survival time. [25]
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