“Evidence suggests that combination treatment of PTD-DBM and valproic acid can also accelerate healing of wounds.
A 2015 study conducted in mice found that the combination of PTD-DBM and valproic acid may help accelerate wound healing.  In this study, researchers created wounds on the dorsal skin of mice and applied PTD-DBM and/or valproic acid on a daily basis in order to stimulate activation of the Wnt/β-catenin pathway. As a positive control, a separate group of mice received epidermal growth factor (EGF), a currently prescribed wound-healing agent.
Researchers observed that treatment with PTD-DBM or valproic acid accelerated wound healing as efficiently as EGF. However, superior wound healing was observed with combination treatment of PTD-DBM and valproic acid compared with EGF alone. In addition, co-treatment with PTD-DBM and valproic acid was associated with significant reduction in inflammatory cells and increase in collagen (promotes wound healing) compared with other groups. Together, these data suggest that combination treatment of PTD-DBM and valproic acid can significantly improve wound healing.
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