One of the major health concerns worldwide is hard-to-treat wounds such as diabetes-induced skin ulcers and burn injuries. These wounds require long and sterile treatments as they increase the affected individual’s risk for infection and permanent tissue damage. Recently, clinical trials are being conducted to find the ideal treatment for debilitating wounds. Researchers found that small peptides such as Tiger 17 possess potent wound healing capacity via its actions on the production of wound healing agents such as transforming growth factor beta (TGF-β), and positive effects on the stages of healing.
Full thickness dermal wound involves damage to the skin and subcutaneous tissue (fat layer). In one study, Tiger 17, a small peptide containing 11 amino acid residues, has been found to exert wound healing effects in a mouse model of full thickness dermal wound.  Researchers found that Tiger 17 improves the wound healing process by:
Tiger 17 may have beneficial effects on wound healing through its antibiotic properties. In one cell study, researchers found that exposure of various microorganisms such as Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli to Tiger 17 reduced bacterial presence.  In this study, microorganisms were exposed to Tiger 17 and commercial woven-swabs. Results of the study showed that the presence of bacteria was significantly reduced by Tiger 17 compared to control.
A study found that Tiger 17 has the potential to treat non-healing wounds with deeper layers by stimulating the production of collagen, a protein necessary for the maintenance of skin matrix.  This in turn speeds up the formation of granulation tissue (new connective tissue) and microscopic blood vessels at the site of injury during the process of regeneration. Granulation tissue normally forms from the base of a wound, allowing it to fill wounds with deeper layers of almost any size.
In another study, Tiger 17 has been found to improve the wound healing process in mice by promoting migration of keratinocytes and formation of granulation tissue at the site of injury.  Since keratinocytes constitute 90% of the cells of the outermost skin layer (epidermis), migration into the wound can accelerate the healing process. Its additional effect on granulation tissue formation can benefit the overall stages of wound regeneration.
Call 800-277-4041 for a Free Consultation
Genemedics® Health Institute is a global premier institute dedicated to revolutionizing health and medicine through healthy lifestyle education, guidance and accountability in harmony with functional medicine. Our physician-supervised health programs are personally customized to help you reach your health and fitness goals while looking and feeling better than ever.