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Vitamin B12 or also known as cyanocobalamin, is one of the eight B vitamins in B-complex. B12 helps to keep nerves and blood cells healthy, prevent megaloblastic anemia, and is important in the formation of DNA. The body absorbs this vitamin in two steps. The hydrochloric acid in the stomach separates the vitamin B12 from the food, and then the vitamin is combined with a stomach protein called intrinsic factor so that it can be absorbed properly.
Both methylcobalamin and cyanocobalamin are the main forms of vitamin B12. While they are nearly similar in structure, there are major differences between them.
Methylcobalamin is a naturally-occurring form of vitamin B12. It is bioidentical to the vitamin B12 forms that can be found in the body and various food sources. Methylcobalamin occurs in high amounts in organ meats, clams, sardines, beef, tuna, and shellfish. It can also be taken in the form of supplements. In contrast, cyanocobalamin, a synthetic form of vitamin B12 that is commonly used in food fortification, can be found only in supplements.
Another difference between methylcobalamin and cyanocobalamin is their absorption or bioavailability. Methylcobalamin has superior bioavailability compared to cyanocobalamin. This means that your body can absorb it better and it can raise your vitamin B12 levels faster.
Studies suggest that vitamin B12 exerts cardioprotective effects:
Vitamin B12 has also been shown to protect against elevated blood pressure:
A number of studies found that vitamin B12 can help promote fat loss:
Evidence suggests that vitamin B12 also has potent anti-cancer properties:
Vitamin B12 is also essential for brain health according to studies:
Studies also report that vitamin B12 is essential for optimal eye function and prevention of eye disorders
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