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Contrave

Author: Dr. George Shanlikian, M.D.  |   Last Updated: May 22nd, 2025

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Potential Health Benefits of Contrave

Contrave benefits include appetite suppression and reduced cravings by targeting the brainā€™s reward system, helping with long-term weight management. It combines bupropion and naltrexone to support weight loss when paired with diet and exercise.

  • Promotes weight loss [2-22]
  • Wards off depression [23-36]
  • Reduces blood sugar levels [2, 37-38]
  • Improves sexual function [39-47]
  • Improves cholesterol levels [48-50]
  • Treats cigarette addiction [51-57]

Key Takeaways

  • Appetite Control ā€“ Contrave helps reduce hunger and food cravings by acting on the brainā€™s reward and hunger-regulating centers.
  • Combination Therapy ā€“ It contains bupropion and naltrexone, which work together to support weight loss efforts.
  • Prescription-Only ā€“ Contrave is available by prescription and is intended for individuals with obesity or overweight conditions with weight-related health risks.
  • Lifestyle Support ā€“ It is most effective when used alongside a reduced-calorie diet and increased physical activity.
  • Potential Side Effects ā€“ Common side effects include nausea, headache, dizziness, and insomnia, and it may not be suitable for individuals with certain medical conditions.

What is Contrave?

Contrave is an FDA-approved drug for adults with a body mass index (BMI) of 30 or higher who wants to lose weight. In some cases, doctors recommend this drug for patients with a BMI of 27 or higher who have one or more weight-related conditions or illnesses, such as hypertension, high cholesterol, or type 2 diabetes. [1] The active ingredients in contrave are bupropion, an antidepressant, and naltrexone, a drug used to combat opioid addiction.

How Contrave Works

The exact neurochemical mechanism by which contrave exerts its weight loss effects is by affecting the function of the hypothalamus, the hunger center of the brain. This, in turn, promotes satiety, reduces food intake, and boosts energy expenditure. As one of the notable weight loss products, the combination of bupropion and naltrexone also works on the mesolimbic pathway, the brain network that provides rewarding feelings. By regulating this pathway, food-seeking behaviors will be significantly reduced.

Chemical Structure of Contrave

Contrave

Research on Contrave

Promotes Weight Loss

Promotes Weight Loss

Taking this medicine, Contrave, promotes weight loss by targeting the brain’s hunger and reward centers with a combination of bupropion and naltrexone. Bupropion helps reduce appetite and boost energy levels, while naltrexone curbs cravings, making it easier to maintain a calorie deficit and achieve long-term weight management. Taking this medicine consistently, as prescribed, can enhance its effectiveness, but it should be combined with a healthy diet and regular exercise for the best results.

  1. In overweight/obese individuals with type 2 diabetes, administration of 32 mg naltrexone sustained-release (SR)/360 mg bupropion SR (NB) resulted in significantly greater weight reduction. [2]
  2. In non-diabetic patients, three phase 3 trials of naltrexone SR plus bupropion SR (NB) demonstrated significant weight loss without any adverse side effects. [3-5]
  3. When combined with lifestyle intervention and modest calorie reduction, the naltrexoneā€“bupropion combination appears to achieve clinically significant weight loss (over 5% of total body weight)after 6 months to 1 year of treatment. [6]
  4. A study found that contrave treatment was associated with 3 to 7% weight loss and improvements in obesity-related comorbidities and cardiovascular risk factors. [7]
  5. Patients who received 1 year of naltrexone ER/bupropion ER combination therapy with greater than 5% weight lost were likely to maintain clinically significant results. [8]
  6. In overweight and obese patients, naltrexone/bupropion (NB) combination therapy was associated with significantly greater weight loss. [9]
  7. In patients with uncomplicated obesity, combined bupropion and naltrexone therapy caused gradual sustained weight loss over 48 weeks. [10]
  8. In middle-aged white females, contrave treatment significantly reduced weight. [11-13]
  9. In obese mice, contrave significantly reduced weight by increasing the activity of POMC cells, which are peptides that play an integral role in weight regulation. [14]
  10. Direct injection of bupropion and naltrexone in mice produced a greater reduction in food intake. [15-16]
  11. In obese patients, contrave treatment reduced body fat and visceral adipose tissue. [17]
  12. A study found that contrave has a greater weight loss efficacy than other FDA-approved drugs for obesity, such as orlistat and lorcaserin. [18]
  13. Studies also found that contrave has favorable effects on obesity, medication-related weight gain, and binge eating behaviors. [19-22]

Wards Off Depression

Wards Off Depression

Contrave, a combination of bupropion and naltrexone, may help ward off depression by influencing brain chemicals involved in mood regulation. Bupropion, an antidepressant, boosts dopamine and norepinephrine levels, while naltrexone may enhance endorphin activity, potentially improving mood and reducing emotional eating.

  1. An analysis of several studies found that there is a strong correlation between obesity and depression, suggesting that weight loss treatment with contrave can have positive effects on mood. [23-31]
  2. In overweight/obese women with major depressive disorder, contrave therapy for 24 weeks was associated with improvement in depressive symptoms. [32]
  3. A large pooled analysis of 5 clinical trials found that contrave was associated with lesser depressive symptoms and psychiatric adverse events compared to placebo. [33-34]
  4. In patients with major depression, treatment with contrave reduced binge eating, a common symptom of depression. [35]
  5. Administration of low-dose naltrexone in combination with bupropion in patients with major depressive disorder significantly reduced the incidence of relapse and recurrence. [36]

Reduces Blood Sugar Levels

Taking this medicine, Contrave, may help lower blood sugar levels by supporting weight loss, which in turn improves insulin sensitivity and glucose metabolism. The combination of bupropion and naltrexone also helps regulate appetite and energy balance, making it easier to manage blood sugar over time. By taking this medicine along with a healthy diet and regular exercise, individuals may see even greater improvements in overall metabolic health.

  1. In overweight and obese patients with type 2 diabetes, treatment with 32 mg naltrexone sustained-release (SR)/360 mg bupropion SR (NB) was associated with improvement in blood sugar control as evidenced by a greater reduction in hemoglobin A1c (HbA1c). [2]
  2. In diabetic patients, naltrexone/bupropion therapy decreased HbA1c approximately 0.5% more than placebo. [37]
  3. In overweight and obese patients, contrave also decreased major cardiovascular risk factors such as high blood sugar. [38]

Improves Sexual Function

Contrave (a combination of bupropion and naltrexone) may improve sexual function indirectly by promoting weight loss, enhancing mood, and increasing energy levels. Bupropion, one of its active ingredients, is known for its potential to boost libido and counteract sexual dysfunction often associated with obesity and depression.

  1. Studies suggest that obesity is linked with greater impairment in sexual function, suggesting that losing weight through contrave supplementation can have a positive impact on sexual health. [39-42]
  2. Bupropion, the component of contrave, has been reported to have proā€sexual effects. [43-46]
  3. In obese patients, administration of contrave significantly improved sexual function as well as the quality of life. [47]

Improves Cholesterol Levels

Contrave may help improve cholesterol levels indirectly by promoting weight loss. As body weight decreases, levels of LDL (bad cholesterol) and triglycerides often decline, while HDL (good cholesterol) may increase, reducing the risk of cardiovascular issues.

  1. In obese patients, naltrexone/bupropion combination significantly reduced the levels of low-density lipoprotein (bad cholesterol) and increased the levels of high-density lipoprotein (good cholesterol). [48]
  2. In overweight and obese patients, daily treatment with contrave increased high-density lipoprotein cholesterol and decreased triglycerides. [49]
  3. In obese adults undergoing weight management, contrave administration also increased high-density lipoprotein cholesterol. [50]

Treats Cigarette Addiction

Contrave may help treat cigarette addiction due to its bupropion component, which is commonly used to aid smoking cessation. Bupropion works by influencing neurotransmitters like dopamine and norepinephrine, reducing cravings and withdrawal symptoms associated with nicotine dependence. Additionally, taking this medicine can help regulate the brain’s reward system, making smoking less satisfying over time. While Contrave is primarily used for weight loss, its effects on cravings and impulse control may provide additional benefits for those trying to quit smoking.

  1. A preliminary investigation of the combination of naltrexone and bupropion as a treatment for cigarette addiction showed increased smoking cessation rates. [51]
  2. Smokers who received contrave treatment for 7 weeks reported reduced nicotine withdrawal. [52]
  3. A study found that both naltrexone and bupropion can help improve adherence to smoking cessation interventions. [53]
  4. One clinical trial found that subjects treated with low-dose naltrexone combined with bupropion stopped cigarette smoking with lesser weight gain. [54]
  5. In overweight or obese smokers, combination therapy of naltrexone and bupropion was associated with decreased nicotine use, limited nicotine withdrawal symptoms, and no significant weight gain. [55]

Associated Side Effects of Contrave

Taking this medicine may cause some side effects, although they are very uncommon. There have been reports of patients experiencing certain symptoms while using Contrave, but these cases were not definitively linked to the medication and could have been coincidental. However, to ensure transparency, these potential side effects are still noted. Itā€™s important to monitor any changes while on Contrave and consult a healthcare professional if any concerns arise.

Side effects associated with contrave may include the following:

  • Constipation
  • Diarrhea
  • Dizziness
  • Dry mouth
  • Headache
  • Insomnia
  • Nausea
  • Vomiting

Contrave Dosage

The recommended Contrave dosage follows a gradual titration schedule to minimize side effects. Patients typically start with one tablet in the morning for the first week. The dosage increases weekly until reaching the maintenance dose of two tablets taken twice daily, totaling four tablets per day.

It is important to take Contrave as prescribed and avoid crushing, chewing, or splitting the tablets. The medication should be taken with food but not high-fat meals, as this can increase the risk of side effects. If a dose is missed, patients should not double up but instead take the next scheduled dose as usual.

Healthcare providers may adjust the dosage based on an individualā€™s response and tolerance. Patients should regularly consult their doctor to monitor progress and address any concerns. If significant side effects occur, the provider may modify or discontinue the medication as needed.

Weight Loss Pill Contrave

Contrave is a prescription weight loss pill that combines two active ingredients, bupropion and naltrexone, to help manage weight in adults with obesity or overweight conditions. It works by targeting the brain’s hunger and reward centers, reducing appetite and food cravings. When combined with a reduced-calorie diet and regular exercise, Contrave can support long-term weight management.

One of the key benefits of Contrave is its dual-action approach, which helps individuals control both emotional eating and physical hunger. Bupropion, an antidepressant, can enhance metabolism and energy levels, while naltrexone, commonly used for addiction treatment, helps regulate cravings. This combination makes it particularly useful for those who struggle with compulsive eating habits.

However, like any medication, Contrave comes with potential side effects, including nausea, headache, dizziness, and an increased heart rate. It is not suitable for individuals with uncontrolled hypertension, seizure disorders, or a history of opioid use. Consulting a healthcare provider is essential to determine if Contrave is a safe and effective option for weight loss.

Contrave Generic

Contrave is a brand-name prescription medication used for weight management, but its generic equivalent, bupropion/naltrexone, offers the same active ingredients at a potentially lower cost. The combination of these two medications helps regulate appetite and cravings by targeting the brainā€™s reward and hunger centers. While the generic version may not always be available due to patent protections, it provides a more affordable alternative when offered.

The generic form, like Contrave, combines bupropion, an antidepressant that also aids in weight loss, and naltrexone, which reduces cravings and addictive behaviors. Together, they help individuals struggling with obesity or overweight conditions, especially when combined with a reduced-calorie diet and increased physical activity. Patients considering the generic should ensure it is FDA-approved to guarantee the same safety and efficacy as the brand-name drug.

Cost savings are a major advantage of using a generic version, making long-term treatment more accessible to patients. However, availability may vary depending on location and pharmacy stock, so checking with a healthcare provider or pharmacist is recommended. Whether using the brand-name Contrave or its generic, proper medical supervision is essential to monitor potential side effects and ensure safe, effective weight management.

Contrave and Alcohol

Contrave is a prescription weight-loss medication that combines bupropion and naltrexone to help regulate appetite and cravings. Since bupropion affects neurotransmitters in the brain, and naltrexone is commonly used to treat alcohol dependence, combining Contrave with alcohol can pose risks. Drinking while taking Contrave may increase the likelihood of side effects such as dizziness, drowsiness, nausea, and mood changes.

Alcohol can also interfere with Contraveā€™s effectiveness by counteracting its appetite-suppressing effects and worsening side effects like increased blood pressure or seizures. Bupropion, one of Contraveā€™s active ingredients, is known to lower the seizure threshold, and alcohol withdrawal or binge drinking can further heighten this risk. Those with a history of alcohol use disorder should be particularly cautious, as naltrexone in Contrave may alter alcoholā€™s effects, potentially reducing tolerance and increasing the chance of intoxication.

Due to these concerns, healthcare providers often recommend limiting or avoiding alcohol while taking Contrave. If you choose to drink, itā€™s best to do so in moderation and monitor your body’s response carefully. Always consult with a doctor before mixing alcohol with Contrave, as individual risk factors such as medical history and current health conditions can influence safety.

Contrave vs Wellbutrin

Contrave and Wellbutrin are both medications that affect brain chemistry, but they serve different primary purposes. Contrave is a weight loss medication that combines bupropion (the active ingredient in Wellbutrin) with naltrexone to help control appetite and food cravings. Wellbutrin, on the other hand, is primarily prescribed for depression and smoking cessation, as it influences dopamine and norepinephrine levels to improve mood and motivation.

While both medications contain bupropion, their effects and uses differ significantly. Contraveā€™s combination with naltrexone helps regulate the brainā€™s reward system to reduce overeating, making it effective for weight management. In contrast, Wellbutrin is used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD), with some off-label use for ADHD. Despite their different purposes, both medications can have similar side effects, including insomnia, dry mouth, and increased heart rate.

Choosing between Contrave and Wellbutrin depends on individual health goals and medical history. If weight loss is the primary concern, Contrave may be a better option due to its appetite-suppressing effects. However, if treating depression or quitting smoking is the main goal, Wellbutrin is more appropriate. Consulting a healthcare provider is essential to determine the best choice based on personal needs and potential risks.

Contrave Contraindications

Contrave contraindications include a history of seizures, as the medication lowers the seizure threshold, increasing the risk of convulsions. Individuals with eating disorders such as bulimia or anorexia nervosa should also avoid Contrave due to the heightened likelihood of seizures associated with bupropion, one of its active ingredients. Additionally, those undergoing abrupt discontinuation of alcohol, benzodiazepines, barbiturates, or antiepileptic drugs are at a higher risk of seizures and should not use Contrave.

Another key contraindication is uncontrolled hypertension, as Contrave can elevate blood pressure and heart rate. Individuals with a history of cardiovascular disease, such as recent heart attack or stroke, should also avoid this medication due to potential cardiovascular risks. Furthermore, Contrave is not recommended for those with severe liver or kidney impairment, as these conditions can alter the metabolism of the drug, leading to increased side effects.

Contrave should not be used by individuals taking monoamine oxidase inhibitors (MAOIs) or those who have used them within the past 14 days, as this combination can lead to dangerous increases in blood pressure. Additionally, people with a known allergy to bupropion or naltrexone, the active ingredients in Contrave, should not take this medication due to the risk of severe allergic reactions. Pregnant women should also avoid Contrave, as weight loss medications are not recommended during pregnancy and may pose risks to fetal development.

Switching from Wellbutrin to Contrave

Switching from Wellbutrin to Contrave requires careful consideration, as both medications contain bupropion, but Contrave also includes naltrexone. Since bupropion affects dopamine and norepinephrine levels, while naltrexone influences the brainā€™s reward system, the transition should be managed under medical supervision to minimize side effects and ensure proper dosing. Gradually adjusting Wellbutrin while introducing Contrave can help reduce the risk of overstimulation, insomnia, or nausea.

Patients switching to Contrave may notice changes in appetite, weight, and mood, as the medication is specifically designed for weight management. While Wellbutrin can sometimes lead to weight loss as a side effect, Contrave is formulated to enhance appetite control and reduce food cravings. However, side effects such as nausea, dizziness, or an increased heart rate may occur, especially during the initial adjustment period.

To ensure a smooth transition, healthcare providers typically tailor the dosing schedule based on individual response and tolerance. Itā€™s important to monitor any changes in mood, energy levels, or potential side effects, as the combination of bupropion and naltrexone can affect each person differently. Open communication with a doctor is key to managing the switch effectively and achieving the desired health outcomes.

Food to Avoid on Contrave

When taking Contrave, it’s important to avoid high-fat meals, as they can increase the absorption of the medication and raise the risk of side effects like nausea and dizziness. Fatty foods such as fried items, creamy sauces, and fast food can also contribute to weight gain, which contradicts the purpose of using Contrave for weight management. Instead, opting for lean proteins, whole grains, and vegetables can support your weight loss goals while minimizing adverse effects.

Sugary and processed foods should also be limited while on Contrave. Excess sugar, found in sweets, sodas, and baked goods, can lead to blood sugar spikes and increased cravings, making weight loss more challenging. Highly processed foods, like chips and packaged snacks, often contain unhealthy fats and additives that can interfere with the appetite-regulating effects of the medication. Choosing nutrient-dense, whole foods can help maintain stable energy levels and support a healthier metabolism.

Alcohol is another substance to avoid while taking Contrave. Drinking alcohol can increase the risk of serious side effects, including dizziness, drowsiness, and mood changes. Since Contrave affects the brainā€™s reward system, alcohol consumption may worsen these effects or reduce the medicationā€™s ability to control cravings. Staying hydrated with water, herbal teas, or other non-sugary beverages is a safer choice for overall well-being.

Contrave Tablets

Contrave tablets are a prescription medication used for weight management in adults with obesity or overweight individuals who have weight-related health conditions. They contain a combination of naltrexone and bupropion, which work together to reduce appetite and control cravings. Contrave is most effective when combined with a reduced-calorie diet and increased physical activity.

The active ingredients in Contrave target brain pathways involved in hunger and reward, helping to regulate eating behaviors. Bupropion, an antidepressant, influences dopamine and norepinephrine levels, which may help with appetite suppression, while naltrexone, typically used for addiction treatment, affects opioid receptors to reduce cravings. This dual-action mechanism makes Contrave a unique option for individuals struggling with weight loss.

Although Contrave can be effective, it may cause side effects such as nausea, constipation, headache, or dizziness. It is not suitable for individuals with uncontrolled high blood pressure, seizure disorders, or those taking opioid medications. Patients should consult their healthcare provider to determine if Contrave is the right choice for their weight loss goals.

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FAQ

What does Contrave do for weight loss?

Contrave helps with weight loss by reducing appetite and controlling cravings through its combination of naltrexone and bupropion, which target brain pathways involved in hunger and reward. However, some individuals may experience an allergic reaction to its ingredients. It is important to be aware of potential side effects, including an allergic reaction, which may require immediate medical attention. If you develop symptoms of an allergic reaction, such as rash, swelling, or difficulty breathing, seek medical help promptly.

Is Contrave as effective as Ozempic?

Ozempic (semaglutide) is generally more effective for weight loss than Contrave, as it directly affects insulin regulation and appetite suppression, leading to greater weight reduction in clinical studies. However, some individuals may experience serious skin reactions, which should be monitored and reported to a healthcare provider if they occur.

Is Contrave the same as Wellbutrin?

No, Contrave is not the same as Wellbutrin. However, it contains bupropion, the active ingredient in Wellbutrin, along with naltrexone to enhance weight loss effects. If you have a missed dose, take it as soon as you remember unless it is close to your next scheduled dose. Avoid doubling up on doses to make up for a missed dose to prevent potential side effects.

How much weight can you lose on Contrave?

No, Contrave is not the same as Wellbutrin. However, it contains bupropion, the active ingredient in Wellbutrin, along with naltrexone to enhance weight loss effects. If you have a missed dose, take it as soon as you remember unless it is close to your next scheduled dose. Avoid doubling up on doses to make up for a missed dose to prevent potential side effects.

Which is better, Contrave or Ozempic?

Ozempic is generally more effective for weight loss, but Contrave may be a better option for those who cannot take GLP-1 receptor agonists or prefer an alternative approach. However, individuals with bipolar disorder should consult their healthcare provider before using Contrave, as it contains bupropion, which may affect mood stability. Additionally, those with a history of bipolar disorder need careful monitoring to prevent potential mood-related side effects.

Does Contrave really work for weight loss?

Yes, Contrave has been shown to help people lose weight, especially when combined with a healthy diet and regular exercise. However, results vary by individual, and some may experience low blood sugar as a side effect. It is important to monitor for symptoms of low blood sugar, such as dizziness, shakiness, or sweating, especially for those with diabetes or on medications that affect blood glucose levels.

What does the drug Contrave do?

Contrave is a prescription weight-loss medication that works by reducing appetite and food cravings through its combination of naltrexone and bupropion. However, some individuals may experience side effects, including a skin rash. If you notice a skin rash or other allergic reactions while taking Contrave, consult your healthcare provider promptly.

Is Contrave the same as Ozempic?

No, Contrave and Ozempic are different medications. Contrave contains naltrexone and bupropion, while Ozempic contains semaglutide, which is a GLP-1 receptor agonist. It is important to note that both medications may cause side effects, including the risk of a serious allergic reaction. If you experience symptoms of a serious allergic reaction, such as swelling, difficulty breathing, or a severe rash, seek medical attention immediately.

What is the average weight loss with Contrave?

The average weight loss with Contrave is around 5%ā€“10% of body weight over 6ā€“12 months, depending on diet, exercise, and adherence to the medication. It is important to discuss with your doctor how Contrave may interact with other medicines you are taking. Some other medicines could affect its effectiveness or increase the risk of side effects.

Is Contrave or Ozempic better?

Ozempic is typically more effective for weight loss, but Contrave may be a suitable alternative for individuals who cannot use GLP-1 receptor agonists. It is important to discuss with your healthcare provider how Contrave interacts with other medicines you may be taking. Additionally, some other medicines could affect the effectiveness or safety of both Ozempic and Contrave.

How much does the diet pill Contrave cost?

Contrave costs around $99 per month with a savings program, but without insurance or discounts, it can range from $200ā€“$400 per month. It is important to consider potential drug interactions when taking Contrave, as certain medications may affect its effectiveness or increase the risk of side effects. Always consult your doctor about any drug interactions before starting treatment.

How quickly do you lose weight on Contrave?

Some people notice weight loss within the first few weeks, but significant results typically appear after 3ā€“6 months of consistent use. However, some individuals may experience skin reactions as a side effect. If you notice any unusual skin reactions, such as rash or irritation, consult a healthcare professional.

Is Contrave better than Ozempic for weight loss?

No, Ozempic is generally more effective for weight loss than Contrave due to its stronger appetite-suppressing and metabolic effects. However, some individuals may experience chest pain as a side effect, which should not be ignored. If you develop chest pain while using Ozempic, seek medical attention immediately.

Do you gain the weight back after Contrave?

Weight regain is possible after stopping Contrave if lifestyle changes are not maintained, as with most weight-loss medications. Additionally, some individuals may experience suicidal thoughts, especially when first starting the medication or adjusting the dose. It is important to monitor for suicidal thoughts and seek medical attention if any concerning symptoms arise.

Is there a generic for Contrave?

No, there is currently no generic version of Contrave available. If an overdose occurs, contact a poison control center immediately for guidance. In case of severe reactions, seeking help from a poison control center can be crucial for proper medical intervention.

Is there a cheaper alternative to Contrave?

A potential alternative is taking generic naltrexone and bupropion separately, but this should only be done under a doctorā€™s supervision. Individuals with kidney disease should exercise caution and consult their healthcare provider before starting these medications. Since kidney disease can affect how drugs are processed in the body, dosage adjustments may be necessary.

What is the cheapest way to get Contrave?

The cheapest way is to use the Contrave Savings Program, which offers the medication for around $99 per month. Some online telehealth services also offer discounts, but Contrave is not available over the counter. If youā€™re looking for weight loss options over the counter, consider discussing alternatives with your healthcare provider.

What are three common side effects?

Common side effects include nausea, constipation, and headache. Although Contrave is not a narcotic medicine, it contains bupropion, which affects brain chemistry. Unlike a narcotic medicine, it does not carry the same risk of dependency but should still be used under medical supervision.

What to avoid while on Contrave?

Avoid high-fat meals when taking Contrave, as they can increase the risk of side effects, including trouble sleeping. Also, avoid alcohol and opioid medications, as they may worsen side effects or lead to complications. If you experience trouble sleeping, consider taking Contrave earlier in the day or consulting your healthcare provider for guidance.

How much alcohol can I drink on Contrave?

It is best to avoid alcohol while taking Contrave, as it can increase the risk of seizures and other side effects. Additionally, it is not known whether Contrave passes into breast milk, so nursing mothers should consult their doctor before using it. If you are breastfeeding, discuss the potential risks of breast milk exposure to the medication with your healthcare provider.

Can you drink alcohol while taking bupropion?

Drinking alcohol while taking bupropion is not recommended, as it can increase the risk of seizures and mood disturbances. Always read the prescription label carefully for warnings related to alcohol consumption. If you have any concerns, consult your healthcare provider and follow the instructions on the prescription label to ensure safe use of the medication.

Is Contrave hard on the liver?

Contrave can affect liver function, particularly in people with preexisting liver disease, so liver function should be monitored while taking it. Some individuals may experience flu-like symptoms, such as fatigue and body aches, as a side effect. If you notice persistent flu-like symptoms, consult your healthcare provider to rule out any serious complications.

Are Contrave and Wellbutrin the same thing?

No, but Contrave contains bupropion, which is the active ingredient in Wellbutrin. Wellbutrin is used primarily for depression and smoking cessation, while Contrave is for weight loss. In some cases, dark urine may be a sign of a serious side effect and should be reported to a healthcare provider. If you notice dark urine along with other symptoms like yellowing of the skin or eyes, seek medical attention promptly.

What is better than Contrave for weight loss?

Ozempic, Wegovy, and other GLP-1 receptor agonists are often more effective for weight loss than Contrave. However, some users may experience unusual tiredness as a side effect. If you notice persistent unusual tiredness, it is advisable to consult your healthcare provider.

How much Wellbutrin is in one Contrave pill?

Each Contrave tablet contains 90 mg of bupropion, which is lower than standard Wellbutrin dosages. If you have a history of a head injury, consult your doctor before using Contrave, as bupropion may increase the risk of seizures. Additionally, individuals recovering from a head injury should be cautious when taking medications that affect the central nervous system.

Has anyone lost weight on Wellbutrin?

Yes, some people experience weight loss on Wellbutrin due to its appetite-suppressing effects, though it is not specifically approved for weight loss.

What medications should not be taken with Contrave?

Avoid taking opioid medications, MAO inhibitors, seizure medications, and other drugs that interact with bupropion or naltrexone. If you miss a dose, take it as soon as you remember, unless it is close to your next scheduled dose. Do not double up on doses if you miss a dose, as this may increase the risk of side effects.

Who shouldn't use Contrave?

People with uncontrolled high blood pressure, seizure disorders, opioid use, or a history of eating disorders should not take Contrave. This medication comes in extended release tablets, which affect how the drug is absorbed in the body. It is important to take extended release tablets as prescribed to ensure safe and effective treatment.

What is the black box warning for Contrave?

Contrave carries a black box warning for an increased risk of suicidal thoughts and behaviors due to its bupropion component. It may also interact with certain medicines, potentially increasing the risk of side effects. Before starting Contrave, inform your doctor if you are taking certain medicines that could affect its safety and effectiveness.

What condition is this major contraindication for bupropion use?

Seizure disorders are a major contraindication for bupropion use, as it can lower the seizure threshold. Additionally, certain medicines may interact with bupropion, increasing the risk of seizures. It is important to consult a healthcare provider before taking bupropion, especially if you are using certain medicines that affect the central nervous system.

What happens if you take Contrave without food?

Taking Contrave without food is recommended, as high-fat meals can increase the risk of side effects. Additionally, consuming alcoholic beverages while taking Contrave may heighten the risk of adverse reactions. It is advisable to limit or avoid alcoholic beverages to ensure the medicationā€™s effectiveness and safety.

How do I get the best results from Contrave?

For the best results, take Contrave as prescribed, follow a reduced-calorie diet, exercise regularly, and avoid high-fat meals. Contrave works to decrease appetite, helping individuals manage their food intake more effectively. By targeting brain pathways, it helps decrease appetite and control cravings for improved weight loss results.

Should you take Contrave before or after eating?

Contrave should be taken in the morning and evening, but not with high-fat meals to avoid increased side effects. Some users may experience blurred vision as a side effect, which can affect daily activities. If blurred vision persists or worsens, consult a healthcare professional promptly.

What not to eat while taking Contrave?

Avoid high-fat foods, as they can increase drug absorption and raise the risk of side effects like nausea and eye pain. If you experience symptoms such as severe eye pain, vision changes, or discomfort, consult a healthcare professional promptly.

Does Contrave cause hair thinning?

Hair thinning is not a commonly reported side effect of Contrave, but some individuals may experience hair loss as a rare reaction to bupropion, one of its active ingredients. Additionally, bupropion may contribute to physical dependence in some users. It is important to consult a healthcare provider if concerns about physical dependence arise while taking Contrave.

What is the most common side effect of Contrave?

The most common side effect of Contrave is nausea, especially when first starting the medication. It is important to consult a doctor before using Contrave during pregnancy, as it may affect an unborn baby. Research on its safety for an unborn baby is limited, so medical guidance is essential.

Does bupropion cause hair loss?

Bupropion has been associated with hair loss in some individuals, though it is considered an uncommon side effect. It is also important to store Contrave properly to maintain its effectiveness. Be sure to store Contrave according to the manufacturer’s guidelines to prevent degradation.

Is Contrave better than Wellbutrin?

Contrave and Wellbutrin serve different purposes; Contrave is used for weight loss, while Wellbutrin is primarily prescribed for depression and smoking cessation. Contrave contains bupropion (the active ingredient in Wellbutrin) along with naltrexone, making it more effective for weight loss than Wellbutrin alone.

Can you take Contrave while on Wellbutrin?

No, taking Contrave with Wellbutrin is not recommended because both contain bupropion, increasing the risk of side effects such as seizures. Contrave acts as an appetite suppressant, helping with weight loss by reducing cravings. Combining multiple medications that affect neurotransmitters involved in appetite suppressant mechanisms can heighten the risk of adverse effects.

How many mg of Wellbutrin is in Contrave?

Contrave contains 90 mg of bupropion per tablet, with a maximum daily dose of 360 mg (four tablets). If a dose is missed, it is generally recommended to take the next dose at the scheduled time rather than doubling up. Always follow your healthcare providerā€™s instructions on when to take the next dose to ensure safe and effective use.

How long does it take your body to get used to Contrave?

Most people adjust to Contrave within a few weeks as their body adapts to the medication and side effects become less noticeable. It is important to read the medication guide provided with your prescription to understand potential risks and usage instructions. Always follow the medication guide and consult your doctor if you have concerns about side effects.

How does Contrave make you lose weight?

Contrave affects the brain’s hunger and reward centers, reducing appetite and cravings, which helps control food intake and promotes weight loss. The medication is a combination of two drugs, naltrexone and bupropion, which work together to influence these brain pathways. By using two drugs with complementary effects, Contrave provides a unique approach to weight management.

How to make Contrave more effective?

To maximize the effectiveness of Contrave, combine it with a healthy diet, regular exercise, and behavioral changes such as mindful eating and portion control. However, be aware that in rare cases, Contrave may cause life-threatening side effects. If you experience severe reactions, seek immediate medical attention, as some complications can be life-threatening.

How long does it take for Contrave to work?

Some young adults may start noticing reduced appetite and cravings within the first few weeks, but significant weight loss results typically occur after 12 weeks of use. In clinical studies, young adults and other age groups experienced varying degrees of weight loss depending on factors like adherence and lifestyle changes.

What is the average weight loss on Contrave?

Clinical studies show that people taking Contrave can lose an average of 5% to 10% of their body weight over six months to a year when combined with diet and exercise. However, some individuals may experience side effects, including irregular heartbeat, which should be monitored closely. If you notice symptoms such as dizziness or irregular heartbeat, consult your healthcare provider immediately.

Who should not take Contrave?

Contrave is not recommended for individuals with uncontrolled high blood pressure, seizure disorders, a history of eating disorders, opioid use, or those who are pregnant or breastfeeding.

Is Contrave the same as Ozempic?

No, Contrave and Ozempic are different medications. Contrave is a combination of bupropion and naltrexone, while Ozempic is a GLP-1 receptor agonist (semaglutide) used for diabetes and weight loss.

What does Contrave do to your body?

Contrave influences brain chemicals that regulate appetite and cravings, helping individuals eat less and lose weight over time.

What foods should you not eat while taking Contrave?

It’s best to avoid high-fat meals, as they can increase the absorption of Contrave and the risk of side effects like nausea.

Why can't you eat eggs on Contrave?

There is no strict restriction on eggs, but some people report nausea when consuming high-fat foods, including eggs, especially if cooked in oil or butter.

How to maximize weight loss on Contrave?

For the best results, follow a structured meal plan, exercise regularly, stay hydrated, and track your progress to maintain motivation and consistency.

Can I eat pizza while taking Contrave?

Yes, but itā€™s best to choose a healthier version with whole-grain crust, lean protein, and vegetables while avoiding excessive cheese and processed meats.

What does Contrave tablets do?

Contrave tablets help with weight loss by reducing appetite and controlling food cravings through their effects on brain neurotransmitters.

How fast do you lose weight on Contrave?

Weight loss varies, but some people start noticing changes within a few weeks, with more significant results seen over several months.

How long does it take Contrave to start working?

Contrave starts affecting appetite and cravings within the first few weeks, but noticeable weight loss usually takes a few months.

Should I take Contrave on an Empty Stomach?

Contrave should not be taken on an empty stomach. The medication contains naltrexone and bupropion, both of which can cause nausea if taken without food. To minimize stomach discomfort and improve absorption, it is recommended to take Contrave with a meal, preferably one that contains some fat.

Does contrave cause hair loss?

Contrave is a prescription weight-loss medication that combines bupropion and naltrexone. While hair loss is not a commonly reported side effect, some users have experienced it. This could be due to the effects of weight loss itself, changes in metabolism, or individual reactions to the drugā€™s active ingredients.

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