Thymosin is a hormone secreted by the thymus gland. This powerful hormone serves a vital role in the training and development of a special type of white blood cell known as T-lymphocytes or T cells. In addition, thymosin also assists in the development of antibodies necessary for a strong immune system. The predominant form of thymosin known as thymosin beta 4 is an action, a multi-functional protein that helps muscles and cells move. Thymosin beta 4 also plays a crucial role in tissue regeneration and protection.
Thymosin beta 4 has the ability to increase the number of immune system cells and decrease inflammatory substances. By binding to actin, it promotes the migration and mobilization of stem/progenitor cells, which are special cells that help form new blood vessels (angiogenesis) and stimulate tissue regeneration. Thymosin beta 4 also decreases scar formation by reducing the number of myofibroblasts (cells responsible for wound healing and tissue repair) in wounds.
Thymosin increases the levels of white blood cells and antibodies, thus strengthening the immune system and protecting against a wide array of diseases. Its predominant form thymosin beta 4 has been shown to heighten the immune response through the following important mechanisms:
The human heart can repair itself at a very slow pace. However, muscle and tissue damage caused by a heart attack cannot be repaired. Interestingly, numerous studies show that thymosin beta 4 could be sufficiently used to improve heart health and regenerate heart damage:
Because of its potent regenerative properties, thymosin beta 4 has also been studied for its therapeutic effect on various liver disorders. Studies show that thymosin beta 4 exerts this effect through the following mechanisms:
Emerging evidence suggests that thymosin beta 4 is involved in a wide range of cellular responses that help accelerate wound healing:
Studies show that thymosin beta 4 may help maintain eye health by protecting against injury and accelerating the eye’s regenerative process:
Thymosin beta 4 is widely distributed in the nervous system, suggesting that it has a role in nerve protection and regeneration. Numerous studies show that thymosin beta 4 is beneficial in several types of nerve injuries:
With thymosin beta 4’s role in tissue regeneration and protection, it seems logical that this powerful protein may also be beneficial in supporting brain health. Numerous studies found that thymosin beta 4 may actually help protect against stroke and other brain injuries:
The anti-scarring properties of thymosin beta 4 may also play a role in maintaining lung health. In mice, thymosin beta 4 administration helps counter bleomycin-induced lung damage by suppressing inflammation and preventing lung scarring. 
Not only does thymosin beta 4 protects against nerve injury caused by diabetes, but it also helps stabilize blood sugar levels.  In diabetic mice, thymosin beta 4 ameliorates high blood sugar levels (hyperglycemia) and improves insulin resistance. 
The ability of thymosin to train and develop T cells may also have a positive effect on blood pressure not just on immune function. In mammals, studies show that administration of thymosin induces the growth of the T cell population and thus reduces the autoimmune state, thereby reducing blood pressure. 
The regenerative properties of thymosin beta 4 allow it to stimulate hair growth. This beneficial effect is backed by a number of studies:
Thymosin beta 4 side effects are very uncommon. There have been some side effects associated with the use of this drug wherein the patient had one of the issues listed below at some point while being on thymosin beta 4. However, these side effects weren’t confirmed to be associated with the treatment and could have been a coincidence and not related to the use of thymosin beta 4. Despite this, it was listed as a side effect associated with thymosin beta 4 even though these associated side effects are very uncommon.
Side effects associated with thymosin beta 4 may include the following:
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