Cardarine, also known by GW501516, was initially prescribed for the treatment of various disorders related to elevated cholesterol levels such as atherosclerosis, myocardial infarction, stroke, and other blood vessel diseases. Today, this drug has gained popularity among athletes and bodybuilders due to its ability to improve muscle strength and exercise endurance. Researchers believe that cardarine exerts its beneficial effects by activating the peroxisome proliferator-activated receptor-delta (PPAR-delta) pathway. Activation of the PPAR-delta pathway is associated with increased energy levels, fat reduction, muscle building, increased endurance, and decreased blood levels of cholesterol.
Cardarine works by increasing muscle cell metabolism and decreasing fat deposits by stimulating lipolysis or fat breakdown. Its active ingredient can significantly increase muscle growth and endurance. Cardarine also helps regulate cholesterol levels and maintain liver health. All of these beneficial effects can be attributed to cardarine’s ability to activate the peroxisome proliferator-activated receptor-delta (PPAR-delta) pathway.
Studies show that cardarine does not only increase muscle mass but it can also improve body composition by promoting fat loss:
Evidence also suggests that cardarine regulates muscle metabolism and reprograms muscle fiber types in order to increase muscle mass and strength:
There’s also strong scientific evidence supporting the beneficial effects of cardarine on exercise endurance:
Studies found that cardarine has a positive effect on low density lipoprotein (bad cholesterol) and high-density lipoprotein (good cholesterol):
Studies show that this PPAR-delta activator can boost cognitive health through different important mechanisms:
Studies suggest that cardarine can significantly lower one’s risk for heart disease through the following mechanisms:
There’s also evidence supporting the anti-diabetic properties of cardarine:
Cardarine also has a potential role in protecting against kidney disease according to studies:
Aside from the kidneys, cardarine can also protect against various liver diseases:
The anti-cancer properties of cardarine are backed by a number of studies:
Cardarine side effects are very uncommon. There have been some side effects associated with the use of this drug wherein the patient had one of the issues listed below at some point while being on cardarine. However, the issue wasn’t’ confirmed to be caused by the treatment and could have been a coincidence and not related to the use of cardarine. Despite this, it was listed as a side effect associated with cardarine even these associated side effects are very uncommon.
Side effects associated with cardarine may include the following:
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