Bremelanotide, also known as PT-141, is a powerful peptide (a compound consisting of two or more amino acids) that activates internal pathways in the brain involved in normal sexual responses. This FDA-approved drug is also a melanocortin receptor agonist, which helps activate a type of protein known as melanocortin receptor. It is given by subcutaneous injection (under the skin) using a single use autoinjector pen. Scientific studies report that administration of this peptide has shown promise in various aspects of health.
Sexual dysfunction often affects one’s self-confidence and relationship with partner. Fortunately, this condition is very treatable with bremelanotide. In fact, the FDA approved bremelanotide in June 2019 as a therapeutic option for women with low libido after it showed an increase in sexual desire and reduction in distress in two replicate phase 3 trials involving women with hypoactive sexual desire disorder (HSDD). [1-2] It now joins flibanserin, the only other drug approved by the FDA for the treatment of HSDD in premenopausal women.
Numerous human studies have also shown promising results with regards to the therapeutic benefits of bremelanotide on sexual health:
Steroids are often extremely effective in alleviating pain and inflammation. However, this drug can affect fat metabolism, which ultimately leads to weight gain. Studies show that bremelanotide counteracts steroid induced weight gain in patients who are on chronic steroid therapy. 
In men and women with sexual dysfunction, low mood and depression are very common. Because of the therapeutic benefit of bremelanotide on libido and sexual performance, this powerful peptide has been studied for its mood-enhancing effect. Studies show that bremelanotide exerts its antidepressant and anti-anxiety effects by improving the function of the central nervous system, resulting in improved overall mood. 
Studies show that melanocortin receptor agonists help protect against diabetes and the negative effects of high blood sugar through the following mechanisms:
There is also evidence that melanocortin receptor agonists such as bremelanotide may help correct abnormal lipid levels. In streptozotocin-induced diabetic mice, injection of melanocortin receptor agonist reduces fat formation in the liver, thereby improving abnormal lipid metabolism associated with insulin-deficiency. 
Melanocortin receptor agonists such as bremelanotide may help increase energy levels as well as productivity. Studies show that melanocortin receptor agonists play a critical role in the regulation of food intake and energy expenditure, primarily through regulation of the activity of the sympathetic nervous system. [22-24]
Photoreceptor cell, a specialized type of neuron found in the retina, is particularly vulnerable to high blood sugar levels. Studies show that melanocortin receptor agonists helps preserve eye health by:
Studies show that the melanocortin receptor agonist bremelanotide may also help improve body composition by inducing weight loss:
Recent data have implicated that melanocortin receptor agonists such as bremelanotide may play a role in modulating voluntary ethanol (alcohol) consumption, thereby treating alcohol addiction. In mice, melanocortin receptor agonist administration effectively reduces ethanol drinking, suggesting that it can be a potential therapeutic option for alcohol abuse disorders. [31-33]
Melanocortin receptor agonists such as bremelanotide play a crucial role in strengthening the immune system. Studies show that melanocortin receptor agonists exert its immune boosting effects through the following important mechanisms:
There is increasing evidence that bremelanotide along with other melanocortin receptor agonists may help improve cognitive health. Studies show that they exert this effect through the following mechanisms:
doi:10.1517/14728214.2010.480973. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163612/.</li>
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