GHK-Cu

The human copper-binding peptide GHK-Cu (glycyl-l-histidyl-l-lysine) is a tripeptide found in human plasma, saliva, and urine. It was first discovered by Loren Pickart in 1973 by isolating the tripeptide from the human plasma. GHK-Cu is proposed to speed up the process of wound healing, regulate immune system cell activity, stimulate collagen and glycosaminoglycan synthesis in the skin, promote growth of blood vessels, and exert anti-aging effects via antioxidant and anti-inflammatory properties. Today, GHK-Cu is used as a protective and regenerative ingredient in various skin and hair products.

Overall Health Benefits of GHK-Cu

Accelerates wound healing [1-27]
Reduces signs of skin aging [28-35]
Improves lung health [36-40]
Fights different cancer types [41-44]
Fights hair loss [45-49]
Accelerates nerve regeneration [50-54]
Fights anxiety [55-57]
Combats cognitive dysfunction [58-67]

Proven Health Benefits of GHK-Cu

Accelerates Wound Healing

GHK-Cu plays an integral role in tissue remodeling and other phases of the wound healing process. An overwhelming body of scientific evidence supports the regenerative properties of this tripeptide:

A 2008 study published in the Journal of Biomaterials Science found that GHK-Cu attracts repair cells such as macrophages, mast cells, capillary cells at the site of injury. [1]
In mice, GHK-Cu improved wound healing by promoting cell proliferation and angiogenesis. [2]
A 2015 study published in the Biomed Research International found that GHK-Cu tripeptide acts as a natural modulator of multiple cellular pathways in skin regeneration. [3]
A study found that GHK-Cu improves wound healing by increasing extracellular matrix (ECM) proteins, collagen, glycosaminoglycans, and DNA synthesis. [4]
Studies found that GHK-Cu modulates various aspects of the wound healing process, including attraction of the cells of the immune system, formation of new blood vessels (angiogenesis), and collagen synthesis. [5-8]
In patients with wounds induced by CO2 laser skin resurfacing, GHK-Cu treatment is associated with higher patient satisfaction. [9]
A study also found that GHK-Cu stimulates the breakdown of existing collagens in wounds. [10]
In rats, GHK-Cu improved skin remodeling process by modulating activity of different metalloproteinases, which are enzymes that remodel wounds. [11-12]
A study reported that GHK-Cu improves wound healing by increasing the levels of decorin, a substance that influences tissue tensile strength and prevents scarring. [13-15]
A cell study found that GHK-Cu increases fibroblasts, which are the key cells in skin reparative and renewal processes. [16]
In rabbits, GHK-Cu treatment resulted in better wound contraction, faster development of granular tissue, and improved blood vessel growth. [17]
When given in combination with laser treatment, GHK-Cu increased the formation of new blood vessels and increased the levels of antioxidant enzymes in the dermal wounds. [18-19]
In rats with difficult to heal wounds, such as diabetic wounds, GHK-Cu treatment resulted in faster wound contraction and closure. [20-21]
In pigs with mild thermal burns, GHK-Cu triggered an accelerated healing of the injury. [22]
In animal models, GHK-Cu treatment accelerated closure in both wound chambers and full thickness wounds. [23]
In patients with diabetic ulcers, application of GHK-Cu gel is associated with faster wound closure and lower rate of infection. [24]
In normal human dermal fibroblasts (skin cells), treatment with GHK-Cu accelerated skin cell renewal by decreasing the secretion of transforming growth factor β (TGF-β), a cytokine involved in programmed cell death. [25-26]
A 2015 study published in Bioorganic and Medicinal Chemistry Letters found that GHK-Cu can help accelerate the wound healing process through its antimicrobial properties. [27]

Reduces Signs of Skin Aging

The regenerative properties of GHK-Cu do not only improve the wound healing process but also reduce the signs of skin aging such as wrinkles, fine lines, and other skin imperfections, according to high quality human studies:

In women with mild to advanced signs of photoaging, application of a facial cream containing GHK-Cu for 12 weeks increased skin density and thickness, improved clarity, and reduced laxity, fine lines, and depth of wrinkles. [28]
In women with mild to advanced photodamage, application of GHK-Cu eye cream for 12 weeks reduced lines and wrinkles, increased skin density and thickness, and improved overall skin appearance compared to vitamin K. [29]
In healthy subjects, application of GHK-Cu cream to thigh skin for 12 weeks improved skin laxity, clarity, firmness, density, thickness and appearance, and reduced fine lines, coarse wrinkles and mottled pigmentation compared to vitamin C cream and retinoic acid. [30]
When applied to the skin twice daily for 12 weeks, GHK-Cu cream strongly stimulated the production of keratinocytes (maintain skin tightness). [31]
When applied to aged skin, GHK-Cu improved skin hydration, thickness, elasticity, and contrast by increasing the production of collagen I. [32-33]
In female volunteers, GHK-Cu treatment resulted in a 55.8% reduction in wrinkle volume and a 32.8% reduction in wrinkle depth. [34]
A cell study found that GHK-Cu may help improve skin health by increasing the levels of p63, a putative stem cell marker of the skin. [35]

A 2012 study published in Genome Medicine found that GHK-Cu improves lung tissue regeneration by restoring the activity of genes involved in the TGF-beta pathway (involved in cell growth and other cellular functions). [36]
In patients with chronic obstructive pulmonary disease (COPD), GHK-Cu administration accelerated lung tissue repair by restoring the contraction and remodeling of collagen. [37-38]
GHK-Cu administration in mice protected their lung tissue from lipopolysaccharide-induced acute lung injury by suppressing the infiltration of inflammatory cells. [39]
In mice, GHK-Cu administration reversed bleomycin-induced inflammation and scarring of the lungs. [40]

Fights Different Cancer Types

Evidence suggests that GHK-Cu also has potent anti-cancer properties that can help suppress the growth and reproduction of aggressive cancer cells:

A cell study found that GHK-Cu suppressed 70% of genes involved in the development of aggressive colon cancer. [41]
Another cell study found that treatment of three lines of human cancer cells with GHK-Cu resulted in activation of programmed cell death (apoptosis). [42]
In a mouse model of bone cancer, GHK-Cu strongly inhibited the growth of cancer cells. [43]
A gene study reported that GHK-Cu has the ability to suppress DNA repair of cancer cells. [44]

Fights Hair Loss

There’s also strong scientific evidence that supports the effects of GHK-Cu in stimulating hair growth and preventing age-related hair loss:

Injection of GHK-Cu in shaved mice for 12 days resulted in strong hair growth stimulation at the injection site. [45]
GHK-Cu administration in rats for 3-4 months doubled follicle size and caused 80% increase in the number of hair follicles that are in the anagen or growth phase. [46]
A cell study found that GHK-Cu accelerates hair growth by stimulating dermal papilla cells, which play an integral role in the growth and development of hair follicles. [47]
A cell study assessing the effect of GHK-Cu on human hair growth reported that the treatment stimulated the proliferation of dermal papilla cells. [48]
A study also found that GHK-Cu exhibits more superior hair growth promoting effects than other peptides. [49]

Accelerates Nerve Regeneration

Studies show that GHK-Cu has the capacity to heal the most debilitating nerve injuries:
A study found that GHK-Cu stimulates new blood vessel growth at the site of nerve injury. [50]
Cell studies found that GHK-Cu stimulates nerve outgrowth and restores skin’s innervation by increasing the production of neurotrophic factors. [51-52]
A cell study also found that GHK-Cu sped up the regeneration of nerve fibers by increasing the production of nerve growth factor and the neurotrophins NT-3 and NT-4. [53]
In rats, GHK-Cu injection alleviated programmed cell death of nerve cells in the brain. [54]

Fights Anxiety

A number of studies also found that GHK-Cu exerts anti-anxiety effect that can help improve overall mood:

In rats, injection with GHK-Cu at 0.5 micrograms per kilogram resulted in a significant reduction of fear and anxiety as evidenced by increased amount of time spent exploring in more open and lighted areas of the maze. [55]
In another rat study, GHK-Cu injection produced anti-anxiety effect as evidenced by less time hiding and more time exploring the area in the open field test. [56]
When injected to aggressive rats, GHK-Cu significantly reduced anxiety-like behaviors. [57]

Combats Cognitive Dysfunction

GHK-Cu can prevent cognitive dysfunction induced by Alzheimer’s disease by reducing the brain levels of abnormal sticky compound known as amyloid beta. [58]
GHK-Cu can potentially prevent Alzheimer’s disease by increasing the levels of antioxidant enzymes. [59-60]
GHK-Cu can improve cognitive health by effectively neutralizing damaging oxygen-derived free radicals. [61-62]
By decreasing the pro-inflammatory cytokine TGF-beta, GHK-Cu can prevent the development of Alzheimer’s disease. [63-66]
GHK-Cu can prevent age-related cognitive decline by improving nervous system function. [67]

References:

Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-88.
Wang X, Liu B, Xu Q, et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regen. 2017;25(2):270-278.
Pickart L, Vasquez-Soltero JM, Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2015;2015:648108. doi:10.1155/2015/648108.
Wegrowski Y, Maquart FX, Borel JP. Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-Lhistidyl-L-lysine-Cu2+. Life Sci. 1992;51(13):1049-56.
Arul V, Kartha R, Jayakumar R. A therapeutic approach for diabetic wound healing using biotinylated GHK incorporated collagen matrices. Life Sci. 2007;80(4):275-284.
Maquart FX, Bellon G, Chaqour B, et al. In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds. J Clin Invest. 1993;92(5):2368-2376.
Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP. Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. FEBS Lett. 1988;238(2):343-346.
Pickart L. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969-988.
Miller TR, Wagner JD, Baack BR, Eisbach KJ. Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin. Arch Facial Plast Surg. 2006;8(4):252-9.
Ehrlich P. Symposium on collagen and skin repair. Reims. Sept 1991 (12).
Siméon A, Monier F, Emonard H, Gillery P, Birembaut P, Hornebeck W, Maquart FX. Expression and activation of matrix metalloproteinases in wounds: modulation by the tripeptide-copper complex glycyl-L-histidylL-lysine-Cu2+.J Invest Dermatol. 1999;112(6):957-64.
H. Ehrlich, “Stimulation of skin healing in immunosuppressed rats,” in Proceedings of the Symposium on Collagen and Skin Repair, Reims, France, September 1991.
Sayani K, Dodd CM, Nedelec B, Shen YJ, Ghahary A, Tredget EE, Scott PG. Delayed appearance of decorin in healing burn scars. Histopathology 200; 36(3): 262-272.
Zhang Z, Li XJ, Zhang X, Li YY, Xu WS. Recombinant human decorin inhibits cell proliferation and downregulates TGF-beta production in hypertrophic scar fibroblasts. Burns 2007; 33(5):634-641.
Huang PJ, Huang YC, Su MF, Yang TY, Huang JR, Jiang CP. In vitro observations on the influence of copper peptide aids for the LED photoirradiation of fibroblast collagen synthesis. Photomed Laser Surg. 2007;25(3):183-90.
Cangul IT, Gul NY, Topal A, Yilmaz R. Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits. Vet Dermatol. 2006;17(6):417-23.
Gul NY, Topal A, Cangul IT, Yanik K. The effects of topical tripeptide copper complex and helium-neon laser on wound healing in rabbits. Vet Dermatol. 2008;19(1):7-14.
Arul V, Gopinath D, Gomathi K, Jayakumar R. Biotinylated GHK peptide incorporated collagenous matrix: A novel biomaterial for dermal wound healing in rats. J Biomed Mater Res B Appl Biomater. 2005;73(2):383-91.
Arul V, Kartha R, Jayakumar R. A therapeutic approach for diabetic wound healing using
biotinylated GHK incorporated collagen matrices. Life Sci. 2007;2;80(4):275-84.
Canapp SO Jr, Farese JP, Schultz GS, Gowda S, Ishak AM, Swaim SF, Vangilder J, Lee-Ambrose L, Martin FG. The effect of topical tripeptide-copper complex on healing of ischemic open wounds. Vet Surg. 2003;32(6):515-23.
Counts, D, Hill E, Turner-Beatty M, Grotewiel M, Fosha-Thomas S, Pickart L. Effect of lamin on full thickness wound healing. Fed Am Soc Exp Biol. 1992; A1636.
Pickart L. Compositions for accelerating wound healing in mammals containing cupric salt or complexes with amino acid or peptide. US Patent 5,164,367, 1992.
Mulder GD, Patt LM, Sanders L, et al. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper. Wound Repair Regen. 1994;2(4):259-69.
D. Downey, W. F. Larrabee Jr., V. Voci, and L. Pickart, “Acceleration of wound healing using glycyl-histidyl-lysine copper (II),” Surgical Forum, vol. 25, pp. 573–575, 1985.
Gruchlik A, Chodurek E, Dzierzewicz Z. Effect of GLY-HIS-LYS and its copper complex on TGF-β secretion in normal human dermal fibroblasts. Acta Pol Pharm. 2014;71(6):954-8.
Leyden J., Stephens T., Finkey M., Appa Y., Barkovic S. Skin Care Benefits of Copper Peptide Containing Facial Cream; Proceedings of the American Academy of Dermatology 60th Annual Meeting; New Orleans, LA, USA. 22–27 February 2002; p. 68.
Kukowska M, Kukowska-kaszuba M, Dzierzbicka K. In vitro studies of antimicrobial activity of Gly-His-Lys conjugates as potential and promising candidates for therapeutics in skin and tissue infections. Bioorg Med Chem Lett. 2015;25(3):542-6.
Leyden J., Stephens T., Finkey M., Barkovic S. Skin Care Benefits of Copper Peptide Containing Eye Creams; Proceedings of the American Academy of Dermatology 60th Annual Meeting; New Orleans, LA, USA. 22–27 February 2002; p. 69.
Abdulghani A., Sherr A., Shirin S., Solodkina G., Tapia E., Wolf B., Gottlieb A.B. Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin—A pilot clinical, histologic, and ultrastructural study. Dis. Manag. Clin. Outcomes. 1998;1:136–141. doi: 10.1016/S1088-3371(98)00011-4.
Finkley M., Appa Y., Bhandarkar S. Copper Peptide and Skin. In: Elsner P., Maibach H., editors. Cosmeceuticals and Active Cosmetics: Drugs vs. Cosmetics. Marcel Dekker; New York, NY, USA: 2005. pp. 549–563.
Krüger N., et al. Topische Applikation eines Kupfertripeptidkomplexes: Pilotstudie bei gealterter Haut. J. Dtsch. Dermatol. Ges. 2003;1.
Krüger N., Fiegert L., Becker D., Reuther T., Kerscher M. Zur Behandlung der Hautalterung: Spurenelemente in Form eines Kupfertripeptidkomplexes. Kos. Med. 2003;24:31–33.
Badenhorst T., Svirskis D., Merrilees M., Bolke L., Wu Z. Effects of GHK-Cu on MMP and TIMP Expression, Collagen and Elastin Production, and Facial Wrinkle Parameters. J. Aging Sci. 2016;4:166. doi: 10.4172/2329-8847.1000166.
Kang YA, Choi HR, Na JI, et al. Copper-GHK increases integrin expression and p63 positivity by keratinocytes. Arch Dermatol Res. 2009;301(4):301-6.
Campbell J. D., McDonough J. E., Zeskind J. E., et al. A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK. Genome Medicine. 2012;4, article 67 doi: 10.1186/gm367.
Boo S., Dagnino L. Integrins as modulators of transforming growth factor beta signaling in dermal fibroblasts during skin regeneration after injury. Advances in Wound Care. 2013;2(5):238–246. doi: 10.1089/wound.2012.0394.
Meiners S., Eickelberg O. Next-generation personalized drug discovery: The tripeptide GHK hits center stage in chronic obstructive pulmonary disease. Genome Med. 2012;4:70. doi: 10.1186/gm371.
Park, J.R.; Lee, H.; Kim, S.I.; Yang, S.R. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget 2016, 7, 58405–58417.
Zhou XM, Wang GL, Wang XB, et al. GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition. Front Pharmacol. 2017;8:904. Published 2017 Dec 12. doi:10.3389/fphar.2017.00904.
Hong Y., Downey T., Eu K. W., Koh P. K., Cheah P. Y. A ‘metastasis-prone’ signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics. Clinical and Experimental Metastasis. 2010;27(2):83–90. doi: 10.1007/s10585-010-9305-4.
Matalka L. E., Ford A., Unlap M. T. The tripeptide, GHK, induces programmed cell death in SH-SY5Y neuroblastoma cells. Journal of Biotechnology & Biomaterials. 2012;2, article 144 doi: 10.4172/2155-952X.1000144.
Pickart L., Vasquez-Soltero J. M., Pickart F. D., Majnarich J. GHK, the human skin remodeling peptide, induces anti-cancer expression of numerous caspase, growth regulatory, and DNA repair genes. Journal of Analytical Oncology. 2014;3(2):79–87. doi: 10.6000/1927-7229.2014.03.02.2.
Pickart L, Vasquez-Soltero JM, Margolina A. GHK and DNA: resetting the human genome to health. Biomed Res Int. 2014;2014:151479. doi:10.1155/2014/151479.
Trachey R, Fors TD, Pickart L, Uno H. The hair follicle stimulating properties of peptide copper complexes. Results in C3H mice. Ann N Y Acad Sci. 1991;642:468-4.
Uno H, Kurata S. Chemical agents and peptides affect hair growth. J Invest Dermatol. 1993;101(1 Suppl):143S-147S.
Perez-Meza D, Leavitt M, Trachy R. Clinical evaluation of GraftCyte moist dressings on hair graft viability and quality of healing. Inter. J. Cos. Surg. 1988;6:80-84.
Pyo HK, Yoo HG, Won CH, et al. The effect of tripeptide-copper complex on human hair growth in vitro. Arch Pharm Res. 2007;30(7):834-9.
Available from https://patents.google.com/patent/US9724416.
Lane T.F., Iruela-Arispe M.L., Johnson R.S., Sage E.H. SPARC is a source of copper-binding peptides that stimulate angiogenesis. J. Cell Biol. 1994;125:929–943. doi: 10.1083/jcb.125.4.929.
Sensenbrenner M., Jaros G.G., Moonen G., Meyer B.J. Effect of conditioned media on nerve cell differentiation. Cell. Mol. Life Sci. 1980;36:660–662. doi: 10.1007/BF01970123.
Lindner G., Grosse G., Halle W., Henklein P. The effect of a synthetic tripeptide nervous tissue cultured in vitro. Z. Mikrosk. Anat. Forsch. 1979;93:820–828.
Ahmed M.R., Basha S.H., Gopinath D., Muthusamy J., Jayakumar R.J. Initial upregulation of growth factors and inflammatory mediators during nerve regeneration in the presence of cell adhesive peptide-incorporated collagen tubes. J. Peripher. Nerv. Syst. 2005;10:17–30. doi: 10.1111/j.1085-9489.2005.10105.x.
Zhang H, Wang Y, He Z. Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway. Front Neurosci. 2018;12:644.
Bobyntsev I.I., Chernysheva O.I., Dolgintsev M.E., Smakhtin M.Y., Belykh A.E. Anxiolytic Effects of Gly-His-Lys Peptide and Its Analogs. Bull. Exp. Biol. Med. 2015;156:726–728. doi: 10.1007/s10517-015-2847-3.
Chernysheva O.I., Bobyntsev I.I., Dolgintsev M.E. The tripeptide GLY-HIS-LYS influence on behavior of rats in the test “open field” Adv. Mod. Biol. Sci. 2014;12:357–360.
Sever’yanova L.А., Dolgintsev M.E. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Ra. Bull. Exp. Biol. Med. 2017;164:140–143. doi: 10.1007/s10517-017-3943-3.
Baig MH, Ahmad K, Rabbani G, Choi I. Use of Peptides for the Management of Alzheimer’s Disease: Diagnosis and Inhibition. Front Aging Neurosci. 2018;10:21.
V. Arul, D. Gopinath, K. Gomathi, and R. Jayakumar, “GHK peptide incorporated collagenous matrix: a novel biomaterial for dermal wound healing in rats,” Journal of Biomedical Materials Research, vol. 73, no. 2, pp. 383–391, 2005.
D. M. Miller, D. DeSilva, L. Pickart, and S. D. Aust, “Effects of glycyl-histidyl-lysyl chelated Cu(II) on ferritin dependent lipid peroxidation,” Advances in Experimental Medicine and Biology, vol. 264, pp. 79–84, 1990.
M. Alberghina, G. Lupo, G. La Spina et al., “Cytoprotective effect of copper(II) complexes against ethanol-induced damage to rat gastric mucosa,” Journal of Inorganic Biochemistry, vol. 45, no. 4, pp. 245–259, 1992.
G. Beretta, R. Artali, L. Regazzoni, M. Panigati, and R. M. Facino, “Glycyl-histidyl-lysine (GHK) is a quencher of α,β-4-hydroxy-trans-2-nonenal: a comparison with carnosine. Insights into the mechanism of reaction by electrospray ionization mass spectrometry, 1H NMR, and computational techniques,” Chemical Research in Toxicology, vol. 20, no. 9, pp. 1309–1314, 2007.
G. Beretta, E. Arlandini, R. Artali, J. M. Anton, and R. Maffei Facino, “Acrolein sequestering ability of the endogenous tripeptide glycyl-histidyl-lysine (GHK): characterization of conjugation products by ESI-MSn and theoretical calculations,” Journal of Pharmaceutical and Biomedical Analysis, vol. 47, no. 3, pp. 596–602, 2008.
P. Agostinho, R. A. Cunha, and C. Oliveira, “Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer’s disease,” Current Pharmaceutical Design, vol. 16, no. 25, pp. 2766–2778, 2010.
M. C. McCormack, K. C. Nowak, and R. J. Koch, “The effect of copper tripeptide and tretinoin on growth factor production in a serum-free fibroblast model.,” Archives of Facial Plastic Surgery, vol. 3, no. 1, pp. 28–32, 2001.
S. O. Canapp Jr., J. P. Farese, G. S. Schultz et al., “The effect of topical tripeptide-copper complex on healing of ischemic open wounds,” Veterinary Surgery, vol. 32, no. 6, pp. 515–523, 2003.
Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7).
Pickart L, Vasquez-soltero JM, Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. Brain Sci. 2017;7(2).

Share -

Overall Health Benefits of GHK-Cu

Proven Health Benefits of GHK-Cu

Accelerates Wound Healing

Reduces Signs of Skin Aging

Fights Different Cancer Types

Fights Hair Loss

Accelerates Nerve Regeneration

Fights Anxiety

Combats Cognitive Dysfunction

References:

Success Stories

About

Locations

Our Services

HEALTH LIBRARY

Overall Health Benefits of GHK-Cu

Proven Health Benefits of GHK-Cu

Accelerates Wound Healing

Reduces Signs of Skin Aging

Fights Different Cancer Types

Fights Hair Loss

Accelerates Nerve Regeneration

Fights Anxiety

Combats Cognitive Dysfunction

References:

Success Stories

About

Locations

Our Services

Free Consultation